Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
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[Homology]
Score
hdcHistidine decarboxylase. (675 aa)    
Predicted Functional Partners:
hal
Histidine ammonia-lyase; Belongs to the PAL/histidase family.
     
 0.937
HNMT
Histamine N-methyltransferase.
     
 0.936
LOC111218536
Histamine N-methyltransferase.
     
 0.936
aoc1
Amine oxidase.
     
 0.921
cndp2
Carnosine dipeptidase 2.
   
 
 0.918
th
Tyrosine hydroxylase.
   
 0.633
LOC111216952
Somatostatin.
   
  
 0.630
dpm2
Dolichol phosphate-mannose biosynthesis regulatory protein; Regulatory subunit of the dolichol-phosphate mannose (DPM) synthase complex; essential for the ER localization. Belongs to the DPM2 family.
      
 0.603
kmo
Kynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid.
   
 
 0.594
LOC111224521
Tyrosine hydroxylase 2.
   
 0.590
Your Current Organism:
Seriola dumerili
NCBI taxonomy Id: 41447
Other names: S. dumerili, greater amberjack
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