Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
pak1Non-specific serine/threonine protein kinase. (562 aa)    
Predicted Functional Partners:
PAK2
Non-specific serine/threonine protein kinase.
  
 
0.990
pak2
Non-specific serine/threonine protein kinase.
  
 
0.990
nck2
Cytoplasmic protein.
    
 0.978
nck1
Cytoplasmic protein.
    
 0.978
CDC42
Cell division cycle 42.
   
 0.975
raf1
Raf-1 proto-oncogene, serine/threonine kinase a.
    
0.957
arhgef6
Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6.
   
 0.950
arhgef7
Rho guanine nucleotide exchange factor (GEF) 7a.
   
 0.950
LOC111239915
Rho guanine nucleotide exchange factor (GEF) 7b.
   
 0.950
LOC111240293
Myosin VIa; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
    
  0.941
Your Current Organism:
Seriola dumerili
NCBI taxonomy Id: 41447
Other names: S. dumerili, greater amberjack
Server load: low (32%) [HD]