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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC111218903VANGL planar cell polarity protein 1. (471 aa)    
Predicted Functional Partners:
ENSSDUP00000007556
DIX domain-containing protein.
    
 0.955
LOC111229014
Dishevelled segment polarity protein 3a.
    
 0.955
dvl2
Dishevelled segment polarity protein 2.
    
 0.955
dvl1
Dishevelled segment polarity protein 1a.
    
 0.955
prickle2
Prickle homolog 2b.
    
 0.938
prickle3
Prickle homolog 3.
    
 0.938
LOC111217353
Prickle homolog 2a.
    
 0.935
PRICKLE1
Prickle homolog 1a.
    
 0.934
LOC111216800
Uncharacterized protein.
    
 0.577
ryk
Receptor like tyrosine kinase.
    
 0.552
Your Current Organism:
Seriola dumerili
NCBI taxonomy Id: 41447
Other names: S. dumerili, greater amberjack
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.