cotl1 protein (Seriola dumerili) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

cotl1

Coactosin-like F-actin binding protein 1. (142 aa)

Predicted Functional Partners:

cap2

0.612

cap1

0.612

gak

0.592

capzb

0.557

lcp1

0.452

alox5ap

0.434

sp1

0.434

gpr17

0.428

LOC111225456

0.423

pls3

0.423

Your Current Organism:

Seriola dumerili

NCBI taxonomy Id: 41447
Other names: S. dumerili, greater amberjack

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC111225456	cap1	ENSSDUP00000016542	ENSSDUP00000029074	Plastin 1 (I isoform).	Adenylyl cyclase-associated protein; Belongs to the CAP family.	0.449
LOC111225456	cap2	ENSSDUP00000016542	ENSSDUP00000014702	Plastin 1 (I isoform).	Adenylyl cyclase-associated protein; Belongs to the CAP family.	0.449
LOC111225456	capzb	ENSSDUP00000016542	ENSSDUP00000012256	Plastin 1 (I isoform).	F-actin-capping protein subunit beta; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.	0.733
LOC111225456	cotl1	ENSSDUP00000016542	ENSSDUP00000006078	Plastin 1 (I isoform).	Coactosin-like F-actin binding protein 1.	0.423
alox5ap	cotl1	ENSSDUP00000020553	ENSSDUP00000006078	Arachidonate 5-lipoxygenase-activating protein.	Coactosin-like F-actin binding protein 1.	0.434
cap1	LOC111225456	ENSSDUP00000029074	ENSSDUP00000016542	Adenylyl cyclase-associated protein; Belongs to the CAP family.	Plastin 1 (I isoform).	0.449
cap1	capzb	ENSSDUP00000029074	ENSSDUP00000012256	Adenylyl cyclase-associated protein; Belongs to the CAP family.	F-actin-capping protein subunit beta; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.	0.565
cap1	cotl1	ENSSDUP00000029074	ENSSDUP00000006078	Adenylyl cyclase-associated protein; Belongs to the CAP family.	Coactosin-like F-actin binding protein 1.	0.612
cap1	lcp1	ENSSDUP00000029074	ENSSDUP00000017135	Adenylyl cyclase-associated protein; Belongs to the CAP family.	Lymphocyte cytosolic protein 1 (L-plastin).	0.449
cap1	pls3	ENSSDUP00000029074	ENSSDUP00000019911	Adenylyl cyclase-associated protein; Belongs to the CAP family.	Plastin 3.	0.449
cap2	LOC111225456	ENSSDUP00000014702	ENSSDUP00000016542	Adenylyl cyclase-associated protein; Belongs to the CAP family.	Plastin 1 (I isoform).	0.449
cap2	capzb	ENSSDUP00000014702	ENSSDUP00000012256	Adenylyl cyclase-associated protein; Belongs to the CAP family.	F-actin-capping protein subunit beta; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.	0.565
cap2	cotl1	ENSSDUP00000014702	ENSSDUP00000006078	Adenylyl cyclase-associated protein; Belongs to the CAP family.	Coactosin-like F-actin binding protein 1.	0.612
cap2	lcp1	ENSSDUP00000014702	ENSSDUP00000017135	Adenylyl cyclase-associated protein; Belongs to the CAP family.	Lymphocyte cytosolic protein 1 (L-plastin).	0.449
cap2	pls3	ENSSDUP00000014702	ENSSDUP00000019911	Adenylyl cyclase-associated protein; Belongs to the CAP family.	Plastin 3.	0.449
capzb	LOC111225456	ENSSDUP00000012256	ENSSDUP00000016542	F-actin-capping protein subunit beta; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.	Plastin 1 (I isoform).	0.733
capzb	cap1	ENSSDUP00000012256	ENSSDUP00000029074	F-actin-capping protein subunit beta; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.	Adenylyl cyclase-associated protein; Belongs to the CAP family.	0.565
capzb	cap2	ENSSDUP00000012256	ENSSDUP00000014702	F-actin-capping protein subunit beta; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.	Adenylyl cyclase-associated protein; Belongs to the CAP family.	0.565
capzb	cotl1	ENSSDUP00000012256	ENSSDUP00000006078	F-actin-capping protein subunit beta; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.	Coactosin-like F-actin binding protein 1.	0.557
capzb	lcp1	ENSSDUP00000012256	ENSSDUP00000017135	F-actin-capping protein subunit beta; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.	Lymphocyte cytosolic protein 1 (L-plastin).	0.733