LOC111240019 protein (Seriola dumerili) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

LOC111240019

TIR domain-containing protein. (823 aa)

Predicted Functional Partners:

LOC111226423

0.970

Tirap

0.956

LOC111220968

0.953

tollip

0.924

RAC1

0.913

LOC111227294

0.913

TLR2

0.904

LOC111222405

0.900

ncf4

0.634

LOC111220923

0.593

Your Current Organism:

Seriola dumerili

NCBI taxonomy Id: 41447
Other names: S. dumerili, greater amberjack

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC111220923	LOC111240019	ENSSDUP00000005409	ENSSDUP00000006188	Cathepsin H; Belongs to the peptidase C1 family.	TIR domain-containing protein.	0.593
LOC111220923	Tirap	ENSSDUP00000005409	ENSSDUP00000019148	Cathepsin H; Belongs to the peptidase C1 family.	Toll-interleukin 1 receptor (TIR) domain containing adaptor protein.	0.476
LOC111220923	ncf4	ENSSDUP00000005409	ENSSDUP00000018293	Cathepsin H; Belongs to the peptidase C1 family.	Neutrophil cytosolic factor 4.	0.567
LOC111220968	LOC111222405	ENSSDUP00000023653	ENSSDUP00000002862	Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response.	Toll-like receptor 18.	0.942
LOC111220968	LOC111226423	ENSSDUP00000023653	ENSSDUP00000004175	Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response.	Toll-like receptor 1.	0.592
LOC111220968	LOC111240019	ENSSDUP00000023653	ENSSDUP00000006188	Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response.	TIR domain-containing protein.	0.953
LOC111220968	TLR2	ENSSDUP00000023653	ENSSDUP00000024142	Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response.	Toll like receptor 2.	0.978
LOC111220968	Tirap	ENSSDUP00000023653	ENSSDUP00000019148	Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response.	Toll-interleukin 1 receptor (TIR) domain containing adaptor protein.	0.987
LOC111220968	tollip	ENSSDUP00000023653	ENSSDUP00000015891	Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response.	Toll interacting protein.	0.958
LOC111222405	LOC111220968	ENSSDUP00000002862	ENSSDUP00000023653	Toll-like receptor 18.	Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response.	0.942
LOC111222405	LOC111226423	ENSSDUP00000002862	ENSSDUP00000004175	Toll-like receptor 18.	Toll-like receptor 1.	0.914
LOC111222405	LOC111227294	ENSSDUP00000002862	ENSSDUP00000013384	Toll-like receptor 18.	Uncharacterized protein.	0.913
LOC111222405	LOC111240019	ENSSDUP00000002862	ENSSDUP00000006188	Toll-like receptor 18.	TIR domain-containing protein.	0.900
LOC111222405	RAC1	ENSSDUP00000002862	ENSSDUP00000006537	Toll-like receptor 18.	Rac family small GTPase 1.	0.913
LOC111222405	TLR2	ENSSDUP00000002862	ENSSDUP00000024142	Toll-like receptor 18.	Toll like receptor 2.	0.913
LOC111222405	Tirap	ENSSDUP00000002862	ENSSDUP00000019148	Toll-like receptor 18.	Toll-interleukin 1 receptor (TIR) domain containing adaptor protein.	0.942
LOC111222405	tollip	ENSSDUP00000002862	ENSSDUP00000015891	Toll-like receptor 18.	Toll interacting protein.	0.924
LOC111226423	LOC111220968	ENSSDUP00000004175	ENSSDUP00000023653	Toll-like receptor 1.	Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response.	0.592
LOC111226423	LOC111222405	ENSSDUP00000004175	ENSSDUP00000002862	Toll-like receptor 1.	Toll-like receptor 18.	0.914
LOC111226423	LOC111240019	ENSSDUP00000004175	ENSSDUP00000006188	Toll-like receptor 1.	TIR domain-containing protein.	0.970