gsk3b protein (Seriola dumerili) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

gsk3b

Glycogen synthase kinase 3 beta, genome duplicate b; Belongs to the protein kinase superfamily. (421 aa)

Predicted Functional Partners:

ctnnb1

0.993

LOC111234107

0.990

LOC111216635

0.985

axin1

0.985

AXIN2

0.982

LOC111227124

0.982

LOC111222989

0.976

ENSSDUP00000007556

0.951

LOC111229014

0.951

dvl2

0.951

Your Current Organism:

Seriola dumerili

NCBI taxonomy Id: 41447
Other names: S. dumerili, greater amberjack

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AXIN2	ENSSDUP00000007556	ENSSDUP00000003350	ENSSDUP00000007556	Axin 2.	DIX domain-containing protein.	0.969
AXIN2	LOC111222989	ENSSDUP00000003350	ENSSDUP00000010685	Axin 2.	Uncharacterized protein.	0.974
AXIN2	LOC111229014	ENSSDUP00000003350	ENSSDUP00000018949	Axin 2.	Dishevelled segment polarity protein 3a.	0.969
AXIN2	LOC111234107	ENSSDUP00000003350	ENSSDUP00000020257	Axin 2.	Glycogen synthase kinase binding protein.	0.511
AXIN2	ctnnb1	ENSSDUP00000003350	ENSSDUP00000016896	Axin 2.	Catenin (cadherin-associated protein), beta 1.	0.988
AXIN2	dvl2	ENSSDUP00000003350	ENSSDUP00000029510	Axin 2.	Dishevelled segment polarity protein 2.	0.970
AXIN2	gsk3b	ENSSDUP00000003350	ENSSDUP00000006189	Axin 2.	Glycogen synthase kinase 3 beta, genome duplicate b; Belongs to the protein kinase superfamily.	0.982
ENSSDUP00000007556	AXIN2	ENSSDUP00000007556	ENSSDUP00000003350	DIX domain-containing protein.	Axin 2.	0.969
ENSSDUP00000007556	LOC111216635	ENSSDUP00000007556	ENSSDUP00000019892	DIX domain-containing protein.	Uncharacterized protein.	0.969
ENSSDUP00000007556	LOC111222989	ENSSDUP00000007556	ENSSDUP00000010685	DIX domain-containing protein.	Uncharacterized protein.	0.552
ENSSDUP00000007556	LOC111227124	ENSSDUP00000007556	ENSSDUP00000012776	DIX domain-containing protein.	Axin 2 (conductin, axil).	0.969
ENSSDUP00000007556	LOC111234107	ENSSDUP00000007556	ENSSDUP00000020257	DIX domain-containing protein.	Glycogen synthase kinase binding protein.	0.917
ENSSDUP00000007556	axin1	ENSSDUP00000007556	ENSSDUP00000025689	DIX domain-containing protein.	Axin 1.	0.969
ENSSDUP00000007556	ctnnb1	ENSSDUP00000007556	ENSSDUP00000016896	DIX domain-containing protein.	Catenin (cadherin-associated protein), beta 1.	0.622
ENSSDUP00000007556	gsk3b	ENSSDUP00000007556	ENSSDUP00000006189	DIX domain-containing protein.	Glycogen synthase kinase 3 beta, genome duplicate b; Belongs to the protein kinase superfamily.	0.951
LOC111216635	ENSSDUP00000007556	ENSSDUP00000019892	ENSSDUP00000007556	Uncharacterized protein.	DIX domain-containing protein.	0.969
LOC111216635	LOC111222989	ENSSDUP00000019892	ENSSDUP00000010685	Uncharacterized protein.	Uncharacterized protein.	0.974
LOC111216635	LOC111229014	ENSSDUP00000019892	ENSSDUP00000018949	Uncharacterized protein.	Dishevelled segment polarity protein 3a.	0.969
LOC111216635	LOC111234107	ENSSDUP00000019892	ENSSDUP00000020257	Uncharacterized protein.	Glycogen synthase kinase binding protein.	0.511
LOC111216635	ctnnb1	ENSSDUP00000019892	ENSSDUP00000016896	Uncharacterized protein.	Catenin (cadherin-associated protein), beta 1.	0.988