close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC111223592Pellino E3 ubiquitin protein ligase family member 3. (472 aa)    
Predicted Functional Partners:
irak1
Interleukin-1 receptor-associated kinase 1.
    
 0.805
irak4
Interleukin-1 receptor-associated kinase 4.
    
 0.768
traf6
TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.
   
 0.702
ripk1
Receptor (TNFRSF)-interacting serine-threonine kinase 1, like.
    
 0.601
LOC111224648
UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.
    
 0.543
ube2n
Ubiquitin conjugating enzyme E2 N; Belongs to the ubiquitin-conjugating enzyme family.
    
 0.543
LOC111235132
Ubiquitin-conjugating enzyme E2 variant 1.
    
 0.474
LOC111221654
UBIQUITIN_CONJUGAT_2 domain-containing protein.
    
 0.474
ube2v2
Ubiquitin-conjugating enzyme E2 variant 2.
    
 0.474
LOC111238592
Receptor-interacting serine-threonine kinase 3.
    
 0.466
Your Current Organism:
Seriola dumerili
NCBI taxonomy Id: 41447
Other names: S. dumerili, greater amberjack
Server load: low (36%) [HD]