STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cdk4Cyclin-dependent kinase 4; Belongs to the protein kinase superfamily. (306 aa)    
Predicted Functional Partners:
ccnd1
Cyclin D1; Belongs to the cyclin family.
   
 0.981
LOC111234824
Cyclin N-terminal domain-containing protein; Belongs to the cyclin family.
   
 0.981
LOC111236603
Cyclin-dependent kinase inhibitor 2A/B (p15, inhibits CDK4).
    
 0.978
LOC111224908
Cyclin D2, b; Belongs to the cyclin family.
   
 0.975
LOC111225171
Cyclin D2, a; Belongs to the cyclin family.
   
 0.975
rb1
Retinoblastoma 1.
   
 0.974
cdkn2c
Cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4).
   
 0.973
LOC111233740
Retinoblastoma-like 2 (p130).
   
 0.973
rbl1
Retinoblastoma-like 1 (p107).
   
 0.973
LOC111222077
Cyclin D3; Belongs to the cyclin family.
   
 0.968
Your Current Organism:
Seriola dumerili
NCBI taxonomy Id: 41447
Other names: S. dumerili, greater amberjack
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.