STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
insInsulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (116 aa)    
Predicted Functional Partners:
LOC111231251
Tyrosine-protein kinase receptor.
    
 0.979
LOC111228731
Tyrosine-protein kinase receptor.
    
 0.979
irs2
Insulin receptor substrate 2b.
     
 0.951
LOC111222710
Insulin receptor substrate 2a.
     
 0.951
LOC111233462
Insulin receptor substrate 4a.
     
 0.951
LOC111233019
Si:ch73-335l21.1.
     
 0.951
ide
Insulin-degrading enzyme; Belongs to the peptidase M16 family.
    
 0.939
pdgfrb
Platelet-derived growth factor receptor, beta polypeptide; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.
   
 
 0.923
egfr
Receptor protein-tyrosine kinase.
     
 0.923
LOC111237405
Receptor protein-tyrosine kinase.
     
 0.923
Your Current Organism:
Seriola dumerili
NCBI taxonomy Id: 41447
Other names: S. dumerili, greater amberjack
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