stn1 protein (Seriola dumerili) - STRING interaction network

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stn1

CST complex subunit STN1; Component of the CST complex proposed to act as a specialized replication factor promoting DNA replication under conditions of replication stress or natural replication barriers such as the telomere duplex. The CST complex binds single-stranded DNA with high affinity in a sequence-independent manner, while isolated subunits bind DNA with low affinity by themselves. Initially the CST complex has been proposed to protect telomeres from DNA degradation. However, the CST complex has been shown to be involved in several aspects of telomere replication. (365 aa)

Predicted Functional Partners:

ten1

0.996

ctc1

0.993

pola1

0.973

prim1

0.969

prim2

0.968

fancm

0.948

ENSSDUP00000023101

0.948

pola2

0.944

rpa3

0.935

med25

0.920

Your Current Organism:

Seriola dumerili

NCBI taxonomy Id: 41447
Other names: S. dumerili, greater amberjack

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSSDUP00000023101	fancm	ENSSDUP00000023101	ENSSDUP00000022982	FA complementation group M.	Uncharacterized protein.	0.987
ENSSDUP00000023101	med25	ENSSDUP00000023101	ENSSDUP00000030414	FA complementation group M.	Mediator complex subunit 25.	0.795
ENSSDUP00000023101	pola1	ENSSDUP00000023101	ENSSDUP00000003623	FA complementation group M.	DNA polymerase.	0.902
ENSSDUP00000023101	rpa3	ENSSDUP00000023101	ENSSDUP00000017919	FA complementation group M.	Replication protein A3.	0.960
ENSSDUP00000023101	stn1	ENSSDUP00000023101	ENSSDUP00000006917	FA complementation group M.	CST complex subunit STN1; Component of the CST complex proposed to act as a specialized replication factor promoting DNA replication under conditions of replication stress or natural replication barriers such as the telomere duplex. The CST complex binds single-stranded DNA with high affinity in a sequence-independent manner, while isolated subunits bind DNA with low affinity by themselves. Initially the CST complex has been proposed to protect telomeres from DNA degradation. However, the CST complex has been shown to be involved in several aspects of telomere replication.	0.948
ctc1	pola1	ENSSDUP00000011979	ENSSDUP00000003623	Uncharacterized protein.	DNA polymerase.	0.948
ctc1	pola2	ENSSDUP00000011979	ENSSDUP00000022202	Uncharacterized protein.	DNA polymerase alpha subunit B; Accessory subunit of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which plays an essential role in the initiation of DNA synthesis.	0.815
ctc1	prim1	ENSSDUP00000011979	ENSSDUP00000031283	Uncharacterized protein.	DNA primase; Belongs to the eukaryotic-type primase small subunit family.	0.778
ctc1	prim2	ENSSDUP00000011979	ENSSDUP00000032722	Uncharacterized protein.	DNA primase subunit 2.	0.927
ctc1	stn1	ENSSDUP00000011979	ENSSDUP00000006917	Uncharacterized protein.	CST complex subunit STN1; Component of the CST complex proposed to act as a specialized replication factor promoting DNA replication under conditions of replication stress or natural replication barriers such as the telomere duplex. The CST complex binds single-stranded DNA with high affinity in a sequence-independent manner, while isolated subunits bind DNA with low affinity by themselves. Initially the CST complex has been proposed to protect telomeres from DNA degradation. However, the CST complex has been shown to be involved in several aspects of telomere replication.	0.993
ctc1	ten1	ENSSDUP00000011979	ENSSDUP00000026578	Uncharacterized protein.	TEN1 subunit of CST complex.	0.992
fancm	ENSSDUP00000023101	ENSSDUP00000022982	ENSSDUP00000023101	Uncharacterized protein.	FA complementation group M.	0.987
fancm	med25	ENSSDUP00000022982	ENSSDUP00000030414	Uncharacterized protein.	Mediator complex subunit 25.	0.795
fancm	pola1	ENSSDUP00000022982	ENSSDUP00000003623	Uncharacterized protein.	DNA polymerase.	0.890
fancm	rpa3	ENSSDUP00000022982	ENSSDUP00000017919	Uncharacterized protein.	Replication protein A3.	0.955
fancm	stn1	ENSSDUP00000022982	ENSSDUP00000006917	Uncharacterized protein.	CST complex subunit STN1; Component of the CST complex proposed to act as a specialized replication factor promoting DNA replication under conditions of replication stress or natural replication barriers such as the telomere duplex. The CST complex binds single-stranded DNA with high affinity in a sequence-independent manner, while isolated subunits bind DNA with low affinity by themselves. Initially the CST complex has been proposed to protect telomeres from DNA degradation. However, the CST complex has been shown to be involved in several aspects of telomere replication.	0.948
med25	ENSSDUP00000023101	ENSSDUP00000030414	ENSSDUP00000023101	Mediator complex subunit 25.	FA complementation group M.	0.795
med25	fancm	ENSSDUP00000030414	ENSSDUP00000022982	Mediator complex subunit 25.	Uncharacterized protein.	0.795
med25	stn1	ENSSDUP00000030414	ENSSDUP00000006917	Mediator complex subunit 25.	CST complex subunit STN1; Component of the CST complex proposed to act as a specialized replication factor promoting DNA replication under conditions of replication stress or natural replication barriers such as the telomere duplex. The CST complex binds single-stranded DNA with high affinity in a sequence-independent manner, while isolated subunits bind DNA with low affinity by themselves. Initially the CST complex has been proposed to protect telomeres from DNA degradation. However, the CST complex has been shown to be involved in several aspects of telomere replication.	0.920
pola1	ENSSDUP00000023101	ENSSDUP00000003623	ENSSDUP00000023101	DNA polymerase.	FA complementation group M.	0.902

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