close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC111225454BTB domain containing 6. (548 aa)    
Predicted Functional Partners:
LOC111224075
CULLIN_2 domain-containing protein; Belongs to the cullin family.
    
 0.546
CUL3
Cullin 3; Belongs to the cullin family.
    
 0.546
GAN
Gigaxonin.
     
 0.541
Bbs9
Bardet-Biedl syndrome 9.
    
 0.529
LOC111224398
TIP120 domain-containing protein.
     
 0.526
cand1
Cullin-associated and neddylation-dissociated 1.
     
 0.526
rbx1
Ring-box 1, E3 ubiquitin protein ligase.
    
 0.524
nae1
NEDD8-activating enzyme E1 regulatory subunit; Regulatory subunit of the dimeric UBA3-NAE1 E1 enzyme. E1 activates NEDD8 by first adenylating its C-terminal glycine residue with ATP, thereafter linking this residue to the side chain of the catalytic cysteine, yielding a NEDD8-UBA3 thioester and free AMP. E1 finally transfers NEDD8 to the catalytic cysteine of UBE2M. Belongs to the ubiquitin-activating E1 family. ULA1 subfamily.
     
 0.509
mib2
Mindbomb E3 ubiquitin protein ligase 2.
   
 0.503
bbs7
Bardet-Biedl syndrome 7.
    
 0.493
Your Current Organism:
Seriola dumerili
NCBI taxonomy Id: 41447
Other names: S. dumerili, greater amberjack
Server load: medium (44%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.