close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC111222538Potassium inwardly-rectifying channel, subfamily J, member 1a, tandem duplicate 6. (373 aa)    
Predicted Functional Partners:
cftr
Cystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane. Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelial fluid layer.
   
 0.596
KCNJ16
Potassium voltage-gated channel subfamily J member 16.
  
 
 
0.499
ENSSDUP00000007026
Potassium inwardly-rectifying channel, subfamily J, member 16.
  
 
 
0.496
ENSSDUP00000031251
Uncharacterized protein.
   
  
 0.482
LOC111224506
ATP-binding cassette, sub-family C (CFTR/MRP), member 9.
 
 
 0.423
abcc8
ATP-binding cassette, sub-family C (CFTR/MRP), member 8.
 
 
 0.423
KCNJ15
Potassium voltage-gated channel subfamily J member 15.
  
 
 
0.409
KCNJ10
Potassium voltage-gated channel subfamily J member 10.
  
 
 
0.409
LOC111235671
Uncharacterized protein.
  
 
 
0.409
miox
Myo-inositol oxygenase.
   
  
 0.408
Your Current Organism:
Seriola dumerili
NCBI taxonomy Id: 41447
Other names: S. dumerili, greater amberjack
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.