node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
LOC111217910 | LOC111233015 | ENSSDUP00000007687 | ENSSDUP00000028226 | High mobility group box 2a. | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. | 0.639 |
LOC111217910 | actl6a | ENSSDUP00000007687 | ENSSDUP00000004255 | High mobility group box 2a. | Actin-like 6A; Belongs to the actin family. | 0.615 |
LOC111217910 | actr5 | ENSSDUP00000007687 | ENSSDUP00000027977 | High mobility group box 2a. | Actin related protein 5; Belongs to the actin family. | 0.613 |
LOC111217910 | actr8 | ENSSDUP00000007687 | ENSSDUP00000000601 | High mobility group box 2a. | Actin-related protein 8; Plays an important role in the functional organization of mitotic chromosomes. Exhibits low basal ATPase activity, and unable to polymerize; Belongs to the actin family. ARP8 subfamily. | 0.652 |
LOC111217910 | ercc3 | ENSSDUP00000007687 | ENSSDUP00000029414 | High mobility group box 2a. | Excision repair cross-complementation group 3. | 0.600 |
LOC111217910 | gtf2h1 | ENSSDUP00000007687 | ENSSDUP00000027242 | High mobility group box 2a. | General transcription factor IIH, polypeptide 1. | 0.614 |
LOC111217910 | gtf2h3 | ENSSDUP00000007687 | ENSSDUP00000028973 | High mobility group box 2a. | General transcription factor IIH, polypeptide 3. | 0.598 |
LOC111217910 | polr1e | ENSSDUP00000007687 | ENSSDUP00000030947 | High mobility group box 2a. | RNA polymerase I subunit E. | 0.580 |
LOC111217910 | polrmt | ENSSDUP00000007687 | ENSSDUP00000006036 | High mobility group box 2a. | DNA-directed RNA polymerase; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the phage and mitochondrial RNA polymerase family. | 0.624 |
LOC111217910 | ruvbl1 | ENSSDUP00000007687 | ENSSDUP00000010792 | High mobility group box 2a. | RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. | 0.605 |
LOC111233015 | LOC111217910 | ENSSDUP00000028226 | ENSSDUP00000007687 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. | High mobility group box 2a. | 0.639 |
LOC111233015 | ercc3 | ENSSDUP00000028226 | ENSSDUP00000029414 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. | Excision repair cross-complementation group 3. | 0.638 |
LOC111233015 | gtf2h1 | ENSSDUP00000028226 | ENSSDUP00000027242 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. | General transcription factor IIH, polypeptide 1. | 0.740 |
actl6a | LOC111217910 | ENSSDUP00000004255 | ENSSDUP00000007687 | Actin-like 6A; Belongs to the actin family. | High mobility group box 2a. | 0.615 |
actl6a | actr5 | ENSSDUP00000004255 | ENSSDUP00000027977 | Actin-like 6A; Belongs to the actin family. | Actin related protein 5; Belongs to the actin family. | 0.993 |
actl6a | actr8 | ENSSDUP00000004255 | ENSSDUP00000000601 | Actin-like 6A; Belongs to the actin family. | Actin-related protein 8; Plays an important role in the functional organization of mitotic chromosomes. Exhibits low basal ATPase activity, and unable to polymerize; Belongs to the actin family. ARP8 subfamily. | 0.999 |
actl6a | ruvbl1 | ENSSDUP00000004255 | ENSSDUP00000010792 | Actin-like 6A; Belongs to the actin family. | RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. | 0.996 |
actr5 | LOC111217910 | ENSSDUP00000027977 | ENSSDUP00000007687 | Actin related protein 5; Belongs to the actin family. | High mobility group box 2a. | 0.613 |
actr5 | actl6a | ENSSDUP00000027977 | ENSSDUP00000004255 | Actin related protein 5; Belongs to the actin family. | Actin-like 6A; Belongs to the actin family. | 0.993 |
actr5 | actr8 | ENSSDUP00000027977 | ENSSDUP00000000601 | Actin related protein 5; Belongs to the actin family. | Actin-related protein 8; Plays an important role in the functional organization of mitotic chromosomes. Exhibits low basal ATPase activity, and unable to polymerize; Belongs to the actin family. ARP8 subfamily. | 0.995 |