node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ATP5F1A | LOC111230479 | ENSSDUP00000002144 | ENSSDUP00000008631 | ATP synthase subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane. | Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. | 0.433 |
ATP5F1A | LOC111239888 | ENSSDUP00000002144 | ENSSDUP00000033148 | ATP synthase subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane. | ATP synthase subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane. | 0.543 |
LOC111219522 | LOC111230479 | ENSSDUP00000029367 | ENSSDUP00000008631 | Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. | Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. | 0.608 |
LOC111219522 | atp1b4 | ENSSDUP00000029367 | ENSSDUP00000007873 | Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. | Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. | 0.405 |
LOC111219522 | pln | ENSSDUP00000029367 | ENSSDUP00000006030 | Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. | Cardiac phospholamban; Reversibly inhibits the activity of ATP2A2 in cardiac sarcoplasmic reticulum by decreasing the apparent affinity of the ATPase for Ca(2+). Modulates the contractility of the heart muscle in response to physiological stimuli via its effects on ATP2A2. Modulates calcium re-uptake during muscle relaxation and plays an important role in calcium homeostasis in the heart muscle. The degree of ATP2A2 inhibition depends on the oligomeric state of PLN. | 0.688 |
LOC111224510 | LOC111230479 | ENSSDUP00000004650 | ENSSDUP00000008631 | Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. | Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. | 0.612 |
LOC111224510 | atp1b4 | ENSSDUP00000004650 | ENSSDUP00000007873 | Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. | Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. | 0.405 |
LOC111224510 | pln | ENSSDUP00000004650 | ENSSDUP00000006030 | Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. | Cardiac phospholamban; Reversibly inhibits the activity of ATP2A2 in cardiac sarcoplasmic reticulum by decreasing the apparent affinity of the ATPase for Ca(2+). Modulates the contractility of the heart muscle in response to physiological stimuli via its effects on ATP2A2. Modulates calcium re-uptake during muscle relaxation and plays an important role in calcium homeostasis in the heart muscle. The degree of ATP2A2 inhibition depends on the oligomeric state of PLN. | 0.688 |
LOC111230479 | ATP5F1A | ENSSDUP00000008631 | ENSSDUP00000002144 | Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. | ATP synthase subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane. | 0.433 |
LOC111230479 | LOC111219522 | ENSSDUP00000008631 | ENSSDUP00000029367 | Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. | Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. | 0.608 |
LOC111230479 | LOC111224510 | ENSSDUP00000008631 | ENSSDUP00000004650 | Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. | Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. | 0.612 |
LOC111230479 | LOC111235946 | ENSSDUP00000008631 | ENSSDUP00000020436 | Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. | Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. | 0.611 |
LOC111230479 | LOC111239888 | ENSSDUP00000008631 | ENSSDUP00000033148 | Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. | ATP synthase subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane. | 0.433 |
LOC111230479 | atp1b4 | ENSSDUP00000008631 | ENSSDUP00000007873 | Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. | Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. | 0.412 |
LOC111230479 | atp2b2 | ENSSDUP00000008631 | ENSSDUP00000021806 | Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. | Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. | 0.610 |
LOC111230479 | atp2b3 | ENSSDUP00000008631 | ENSSDUP00000019067 | Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. | Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. | 0.608 |
LOC111230479 | pln | ENSSDUP00000008631 | ENSSDUP00000006030 | Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. | Cardiac phospholamban; Reversibly inhibits the activity of ATP2A2 in cardiac sarcoplasmic reticulum by decreasing the apparent affinity of the ATPase for Ca(2+). Modulates the contractility of the heart muscle in response to physiological stimuli via its effects on ATP2A2. Modulates calcium re-uptake during muscle relaxation and plays an important role in calcium homeostasis in the heart muscle. The degree of ATP2A2 inhibition depends on the oligomeric state of PLN. | 0.968 |
LOC111230479 | tmem165 | ENSSDUP00000008631 | ENSSDUP00000031807 | Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. | GDT1 family protein. | 0.495 |
LOC111235946 | LOC111230479 | ENSSDUP00000020436 | ENSSDUP00000008631 | Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. | Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. | 0.611 |
LOC111235946 | atp1b4 | ENSSDUP00000020436 | ENSSDUP00000007873 | Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. | Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. | 0.405 |