SPATA5 protein (Seriola dumerili) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

SPATA5

Spermatogenesis associated 5. (903 aa)

Predicted Functional Partners:

ubxn7

0.999

ufd1

0.935

derl1

0.931

nsfl1c

0.927

yod1

0.923

ubxn1

0.902

psmb2

0.884

LOC111226164

0.879

faap100

0.855

nploc4

0.855

Your Current Organism:

Seriola dumerili

NCBI taxonomy Id: 41447
Other names: S. dumerili, greater amberjack

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC111226164	SPATA5	ENSSDUP00000002242	ENSSDUP00000010265	Ataxin 3.	Spermatogenesis associated 5.	0.879
LOC111226164	ufd1	ENSSDUP00000002242	ENSSDUP00000002868	Ataxin 3.	Ubiquitin recognition factor in ER associated degradation 1.	0.593
SPATA5	LOC111226164	ENSSDUP00000010265	ENSSDUP00000002242	Spermatogenesis associated 5.	Ataxin 3.	0.879
SPATA5	derl1	ENSSDUP00000010265	ENSSDUP00000015577	Spermatogenesis associated 5.	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	0.931
SPATA5	faap100	ENSSDUP00000010265	ENSSDUP00000005890	Spermatogenesis associated 5.	Si:dkey-57h18.1.	0.855
SPATA5	nploc4	ENSSDUP00000010265	ENSSDUP00000006661	Spermatogenesis associated 5.	NPL4 homolog, ubiquitin recognition factor.	0.855
SPATA5	nsfl1c	ENSSDUP00000010265	ENSSDUP00000025296	Spermatogenesis associated 5.	NSFL1 (p97) cofactor (p47).	0.927
SPATA5	psmb2	ENSSDUP00000010265	ENSSDUP00000028960	Spermatogenesis associated 5.	Proteasome subunit beta.	0.884
SPATA5	ubxn1	ENSSDUP00000010265	ENSSDUP00000022603	Spermatogenesis associated 5.	UBX domain protein 1.	0.902
SPATA5	ubxn7	ENSSDUP00000010265	ENSSDUP00000012354	Spermatogenesis associated 5.	UBX domain protein 7.	0.999
SPATA5	ufd1	ENSSDUP00000010265	ENSSDUP00000002868	Spermatogenesis associated 5.	Ubiquitin recognition factor in ER associated degradation 1.	0.935
SPATA5	yod1	ENSSDUP00000010265	ENSSDUP00000025272	Spermatogenesis associated 5.	YOD1 deubiquitinase.	0.923
derl1	SPATA5	ENSSDUP00000015577	ENSSDUP00000010265	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	Spermatogenesis associated 5.	0.931
derl1	faap100	ENSSDUP00000015577	ENSSDUP00000005890	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	Si:dkey-57h18.1.	0.922
derl1	nploc4	ENSSDUP00000015577	ENSSDUP00000006661	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	NPL4 homolog, ubiquitin recognition factor.	0.922
derl1	nsfl1c	ENSSDUP00000015577	ENSSDUP00000025296	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	NSFL1 (p97) cofactor (p47).	0.947
derl1	ubxn1	ENSSDUP00000015577	ENSSDUP00000022603	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	UBX domain protein 1.	0.976
derl1	ufd1	ENSSDUP00000015577	ENSSDUP00000002868	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	Ubiquitin recognition factor in ER associated degradation 1.	0.966
faap100	SPATA5	ENSSDUP00000005890	ENSSDUP00000010265	Si:dkey-57h18.1.	Spermatogenesis associated 5.	0.855
faap100	derl1	ENSSDUP00000005890	ENSSDUP00000015577	Si:dkey-57h18.1.	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	0.922