STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC111229284Dynamin 2b; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (864 aa)    
Predicted Functional Partners:
gak
Cyclin G associated kinase.
   
 0.982
dnm2
Dynamin 2a; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.
  
  
 
0.900
LOC111217580
Intersectin 2b.
    
 
 0.836
itsn2
Intersectin 2a.
    
 
 0.836
dnajc6
DnaJ (Hsp40) homolog, subfamily C, member 6.
   
 0.725
prkn
E3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins; Belongs to the RBR family. Parkin subfamily.
    
 0.716
itsn1
Intersectin 1 (SH3 domain protein).
    
 
 0.674
pink1
PTEN induced kinase 1.
    
 0.660
ap2a1
AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...]
   
 0.602
LOC111232093
SH3-domain GRB2-like 1b.
   
 0.594
Your Current Organism:
Seriola dumerili
NCBI taxonomy Id: 41447
Other names: S. dumerili, greater amberjack
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.