smyd4 protein (Seriola dumerili) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

smyd4

SET and MYND domain containing 4. (785 aa)

Predicted Functional Partners:

LOC111233015

0.753

smyd5

0.633

eed

0.628

ash2l

0.617

rbbp5

0.613

rogdi

0.611

SMYD3

0.583

cops7a

0.580

psmd3

0.557

mphosph8

0.541

Your Current Organism:

Seriola dumerili

NCBI taxonomy Id: 41447
Other names: S. dumerili, greater amberjack

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC111233015	SMYD3	ENSSDUP00000028226	ENSSDUP00000002239	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.	SET and MYND domain containing 3.	0.874
LOC111233015	psmd3	ENSSDUP00000028226	ENSSDUP00000021598	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.	Proteasome 26S subunit, non-ATPase 3.	0.413
LOC111233015	smyd4	ENSSDUP00000028226	ENSSDUP00000022446	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.	SET and MYND domain containing 4.	0.753
LOC111233015	smyd5	ENSSDUP00000028226	ENSSDUP00000005177	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.	SMYD family member 5.	0.752
SMYD3	LOC111233015	ENSSDUP00000002239	ENSSDUP00000028226	SET and MYND domain containing 3.	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.	0.874
SMYD3	ash2l	ENSSDUP00000002239	ENSSDUP00000032831	SET and MYND domain containing 3.	Ash2 like, histone lysine methyltransferase complex subunit.	0.700
SMYD3	eed	ENSSDUP00000002239	ENSSDUP00000015795	SET and MYND domain containing 3.	Embryonic ectoderm development.	0.628
SMYD3	mphosph8	ENSSDUP00000002239	ENSSDUP00000018721	SET and MYND domain containing 3.	Chromo domain-containing protein.	0.541
SMYD3	psmd3	ENSSDUP00000002239	ENSSDUP00000021598	SET and MYND domain containing 3.	Proteasome 26S subunit, non-ATPase 3.	0.557
SMYD3	rbbp5	ENSSDUP00000002239	ENSSDUP00000026787	SET and MYND domain containing 3.	Retinoblastoma binding protein 5.	0.675
SMYD3	smyd4	ENSSDUP00000002239	ENSSDUP00000022446	SET and MYND domain containing 3.	SET and MYND domain containing 4.	0.583
SMYD3	smyd5	ENSSDUP00000002239	ENSSDUP00000005177	SET and MYND domain containing 3.	SMYD family member 5.	0.590
ash2l	SMYD3	ENSSDUP00000032831	ENSSDUP00000002239	Ash2 like, histone lysine methyltransferase complex subunit.	SET and MYND domain containing 3.	0.700
ash2l	rbbp5	ENSSDUP00000032831	ENSSDUP00000026787	Ash2 like, histone lysine methyltransferase complex subunit.	Retinoblastoma binding protein 5.	0.999
ash2l	smyd4	ENSSDUP00000032831	ENSSDUP00000022446	Ash2 like, histone lysine methyltransferase complex subunit.	SET and MYND domain containing 4.	0.617
ash2l	smyd5	ENSSDUP00000032831	ENSSDUP00000005177	Ash2 like, histone lysine methyltransferase complex subunit.	SMYD family member 5.	0.612
cops7a	rogdi	ENSSDUP00000018796	ENSSDUP00000023759	COP9 constitutive photomorphogenic homolog subunit 7A.	Rogdi atypical leucine zipper.	0.432
cops7a	smyd4	ENSSDUP00000018796	ENSSDUP00000022446	COP9 constitutive photomorphogenic homolog subunit 7A.	SET and MYND domain containing 4.	0.580
eed	SMYD3	ENSSDUP00000015795	ENSSDUP00000002239	Embryonic ectoderm development.	SET and MYND domain containing 3.	0.628
eed	mphosph8	ENSSDUP00000015795	ENSSDUP00000018721	Embryonic ectoderm development.	Chromo domain-containing protein.	0.403