node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
LOC111221857 | TMEM43 | ENSSDUP00000031522 | ENSSDUP00000018241 | Nicalin; May antagonize Nodal signaling and subsequent organization of axial structures during mesodermal patterning. | Uncharacterized protein. | 0.479 |
LOC111221857 | ddost | ENSSDUP00000031522 | ENSSDUP00000004373 | Nicalin; May antagonize Nodal signaling and subsequent organization of axial structures during mesodermal patterning. | Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across t [...] | 0.458 |
LOC111221857 | smpd4 | ENSSDUP00000031522 | ENSSDUP00000023950 | Nicalin; May antagonize Nodal signaling and subsequent organization of axial structures during mesodermal patterning. | Sphingomyelin phosphodiesterase 4. | 0.519 |
LOC111228459 | TMEM43 | ENSSDUP00000011475 | ENSSDUP00000018241 | Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...] | Uncharacterized protein. | 0.418 |
LOC111228459 | ddost | ENSSDUP00000011475 | ENSSDUP00000004373 | Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...] | Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across t [...] | 0.401 |
LOC111228459 | ncln | ENSSDUP00000011475 | ENSSDUP00000001803 | Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...] | Nicalin. | 0.467 |
LOC111228459 | smpd4 | ENSSDUP00000011475 | ENSSDUP00000023950 | Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...] | Sphingomyelin phosphodiesterase 4. | 0.493 |
LOC111236808 | smpd2 | ENSSDUP00000008042 | ENSSDUP00000000116 | Sphingomyelin phosphodiesterase 5. | Sphingomyelin phosphodiesterase 2b, neutral membrane (neutral sphingomyelinase). | 0.930 |
LOC111236808 | smpd4 | ENSSDUP00000008042 | ENSSDUP00000023950 | Sphingomyelin phosphodiesterase 5. | Sphingomyelin phosphodiesterase 4. | 0.567 |
TMEM43 | LOC111221857 | ENSSDUP00000018241 | ENSSDUP00000031522 | Uncharacterized protein. | Nicalin; May antagonize Nodal signaling and subsequent organization of axial structures during mesodermal patterning. | 0.479 |
TMEM43 | LOC111228459 | ENSSDUP00000018241 | ENSSDUP00000011475 | Uncharacterized protein. | Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...] | 0.418 |
TMEM43 | ncln | ENSSDUP00000018241 | ENSSDUP00000001803 | Uncharacterized protein. | Nicalin. | 0.606 |
TMEM43 | smpd4 | ENSSDUP00000018241 | ENSSDUP00000023950 | Uncharacterized protein. | Sphingomyelin phosphodiesterase 4. | 0.597 |
aqr | smpd4 | ENSSDUP00000020723 | ENSSDUP00000023950 | Aquarius intron-binding spliceosomal factor. | Sphingomyelin phosphodiesterase 4. | 0.603 |
cpsf1 | smpd4 | ENSSDUP00000001488 | ENSSDUP00000023950 | Cleavage and polyadenylation specific factor 1. | Sphingomyelin phosphodiesterase 4. | 0.518 |
ddost | LOC111221857 | ENSSDUP00000004373 | ENSSDUP00000031522 | Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across t [...] | Nicalin; May antagonize Nodal signaling and subsequent organization of axial structures during mesodermal patterning. | 0.458 |
ddost | LOC111228459 | ENSSDUP00000004373 | ENSSDUP00000011475 | Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across t [...] | Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...] | 0.401 |
ddost | ncln | ENSSDUP00000004373 | ENSSDUP00000001803 | Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across t [...] | Nicalin. | 0.593 |
ddost | smpd4 | ENSSDUP00000004373 | ENSSDUP00000023950 | Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across t [...] | Sphingomyelin phosphodiesterase 4. | 0.585 |
ncln | LOC111228459 | ENSSDUP00000001803 | ENSSDUP00000011475 | Nicalin. | Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...] | 0.467 |