node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ATP5F1A | atp2a3 | ENSSDUP00000002144 | ENSSDUP00000024729 | ATP synthase subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane. | Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. | 0.441 |
ENSSDUP00000004727 | atp2a3 | ENSSDUP00000004727 | ENSSDUP00000024729 | Myosin, light chain kinase a. | Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. | 0.525 |
LOC111219522 | atp2a3 | ENSSDUP00000029367 | ENSSDUP00000024729 | Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. | Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. | 0.605 |
LOC111219522 | pln | ENSSDUP00000029367 | ENSSDUP00000006030 | Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. | Cardiac phospholamban; Reversibly inhibits the activity of ATP2A2 in cardiac sarcoplasmic reticulum by decreasing the apparent affinity of the ATPase for Ca(2+). Modulates the contractility of the heart muscle in response to physiological stimuli via its effects on ATP2A2. Modulates calcium re-uptake during muscle relaxation and plays an important role in calcium homeostasis in the heart muscle. The degree of ATP2A2 inhibition depends on the oligomeric state of PLN. | 0.688 |
LOC111224510 | atp2a3 | ENSSDUP00000004650 | ENSSDUP00000024729 | Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. | Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. | 0.606 |
LOC111224510 | pln | ENSSDUP00000004650 | ENSSDUP00000006030 | Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. | Cardiac phospholamban; Reversibly inhibits the activity of ATP2A2 in cardiac sarcoplasmic reticulum by decreasing the apparent affinity of the ATPase for Ca(2+). Modulates the contractility of the heart muscle in response to physiological stimuli via its effects on ATP2A2. Modulates calcium re-uptake during muscle relaxation and plays an important role in calcium homeostasis in the heart muscle. The degree of ATP2A2 inhibition depends on the oligomeric state of PLN. | 0.688 |
LOC111234726 | atp2a3 | ENSSDUP00000024935 | ENSSDUP00000024729 | Troponin C type 2 (fast). | Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. | 0.459 |
LOC111235946 | atp2a3 | ENSSDUP00000020436 | ENSSDUP00000024729 | Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. | Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. | 0.607 |
LOC111235946 | pln | ENSSDUP00000020436 | ENSSDUP00000006030 | Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. | Cardiac phospholamban; Reversibly inhibits the activity of ATP2A2 in cardiac sarcoplasmic reticulum by decreasing the apparent affinity of the ATPase for Ca(2+). Modulates the contractility of the heart muscle in response to physiological stimuli via its effects on ATP2A2. Modulates calcium re-uptake during muscle relaxation and plays an important role in calcium homeostasis in the heart muscle. The degree of ATP2A2 inhibition depends on the oligomeric state of PLN. | 0.669 |
atp2a3 | ATP5F1A | ENSSDUP00000024729 | ENSSDUP00000002144 | Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. | ATP synthase subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane. | 0.441 |
atp2a3 | ENSSDUP00000004727 | ENSSDUP00000024729 | ENSSDUP00000004727 | Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. | Myosin, light chain kinase a. | 0.525 |
atp2a3 | LOC111219522 | ENSSDUP00000024729 | ENSSDUP00000029367 | Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. | Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. | 0.605 |
atp2a3 | LOC111224510 | ENSSDUP00000024729 | ENSSDUP00000004650 | Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. | Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. | 0.606 |
atp2a3 | LOC111234726 | ENSSDUP00000024729 | ENSSDUP00000024935 | Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. | Troponin C type 2 (fast). | 0.459 |
atp2a3 | LOC111235946 | ENSSDUP00000024729 | ENSSDUP00000020436 | Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. | Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. | 0.607 |
atp2a3 | atp2b2 | ENSSDUP00000024729 | ENSSDUP00000021806 | Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. | Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. | 0.608 |
atp2a3 | atp2b3 | ENSSDUP00000024729 | ENSSDUP00000019067 | Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. | Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. | 0.605 |
atp2a3 | pln | ENSSDUP00000024729 | ENSSDUP00000006030 | Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. | Cardiac phospholamban; Reversibly inhibits the activity of ATP2A2 in cardiac sarcoplasmic reticulum by decreasing the apparent affinity of the ATPase for Ca(2+). Modulates the contractility of the heart muscle in response to physiological stimuli via its effects on ATP2A2. Modulates calcium re-uptake during muscle relaxation and plays an important role in calcium homeostasis in the heart muscle. The degree of ATP2A2 inhibition depends on the oligomeric state of PLN. | 0.972 |
atp2a3 | tmem165 | ENSSDUP00000024729 | ENSSDUP00000031807 | Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. | GDT1 family protein. | 0.495 |
atp2b2 | atp2a3 | ENSSDUP00000021806 | ENSSDUP00000024729 | Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. | Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. | 0.608 |