STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC111233605Uncharacterized protein. (108 aa)    
Predicted Functional Partners:
LOC111219668
Guanylate cyclase.
   
 
 0.819
LOC111239181
Guanylate cyclase.
   
 
 0.819
npr3
Natriuretic peptide receptor 3.
   
 
 0.772
Tmigd1
Transmembrane and immunoglobulin domain containing 1.
   
  
 0.725
LOC111237013
Emerin (Emery-Dreifuss muscular dystrophy).
      
 0.633
LOC111236830
Guanylate cyclase.
   
 
 0.454
LOC111234372
Guanylate cyclase.
   
 
 0.454
LOC111233425
Guanylate cyclase.
   
 
 0.454
LOC111233471
Guanylate cyclase.
   
 
 0.454
cftr
Cystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane. Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelial fluid layer.
      
 0.436
Your Current Organism:
Seriola dumerili
NCBI taxonomy Id: 41447
Other names: S. dumerili, greater amberjack
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.