STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
BRK1BRICK1 subunit of SCAR/WAVE actin nucleating complex. (75 aa)    
Predicted Functional Partners:
LOC111226543
Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family.
    
 0.999
cyfip1
Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family.
    
 0.998
nckap1
NCK-associated protein 1.
    
 0.996
nckap1l
NCK associated protein 1 like.
    
 0.996
LOC111228794
Abl-interactor 1b.
    
 0.993
ABI1
Abl-interactor 1a.
    
 0.993
arpc3
Actin-related protein 2/3 complex subunit 3; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.
   
 0.990
wasf1
WASP family member 1.
    
 0.987
ARPC4
Actin-related protein 2/3 complex subunit 4; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the mother actin filament; Belongs to the ARPC4 family.
   
 
 0.983
abi2
Uncharacterized protein.
    
 0.982
Your Current Organism:
Seriola dumerili
NCBI taxonomy Id: 41447
Other names: S. dumerili, greater amberjack
Server load: low (22%) [HD]