LOC111239310 protein (Seriola dumerili) - STRING interaction network

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second shell of interactors

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

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Score

LOC111239310

Claudin 23a. (266 aa)

Predicted Functional Partners:

LOC111231759

0.715

ENSSDUP00000023428

0.682

cldn11

0.665

LOC111225662

0.665

LOC111224463

0.660

ENSSDUP00000001877

0.659

ENSSDUP00000001888

0.659

ENSSDUP00000001901

0.659

CLDN10

0.659

LOC111222746

0.659

Your Current Organism:

Seriola dumerili

NCBI taxonomy Id: 41447
Other names: S. dumerili, greater amberjack

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CLDN10	ENSSDUP00000001877	ENSSDUP00000003280	ENSSDUP00000001877	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	Uncharacterized protein.	0.657
CLDN10	ENSSDUP00000001888	ENSSDUP00000003280	ENSSDUP00000001888	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	0.657
CLDN10	ENSSDUP00000001901	ENSSDUP00000003280	ENSSDUP00000001901	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	Uncharacterized protein.	0.657
CLDN10	ENSSDUP00000023428	ENSSDUP00000003280	ENSSDUP00000023428	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	Zgc:136892.	0.691
CLDN10	LOC111222746	ENSSDUP00000003280	ENSSDUP00000012898	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	0.657
CLDN10	LOC111224463	ENSSDUP00000003280	ENSSDUP00000017189	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	0.724
CLDN10	LOC111225662	ENSSDUP00000003280	ENSSDUP00000014331	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	Claudin 11a.	0.676
CLDN10	LOC111231759	ENSSDUP00000003280	ENSSDUP00000018346	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	0.654
CLDN10	LOC111239310	ENSSDUP00000003280	ENSSDUP00000028642	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	Claudin 23a.	0.659
CLDN10	cldn11	ENSSDUP00000003280	ENSSDUP00000004403	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	0.676
ENSSDUP00000001877	CLDN10	ENSSDUP00000001877	ENSSDUP00000003280	Uncharacterized protein.	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	0.657
ENSSDUP00000001877	ENSSDUP00000001888	ENSSDUP00000001877	ENSSDUP00000001888	Uncharacterized protein.	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	0.657
ENSSDUP00000001877	ENSSDUP00000001901	ENSSDUP00000001877	ENSSDUP00000001901	Uncharacterized protein.	Uncharacterized protein.	0.658
ENSSDUP00000001877	ENSSDUP00000023428	ENSSDUP00000001877	ENSSDUP00000023428	Uncharacterized protein.	Zgc:136892.	0.678
ENSSDUP00000001877	LOC111222746	ENSSDUP00000001877	ENSSDUP00000012898	Uncharacterized protein.	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	0.657
ENSSDUP00000001877	LOC111224463	ENSSDUP00000001877	ENSSDUP00000017189	Uncharacterized protein.	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	0.743
ENSSDUP00000001877	LOC111225662	ENSSDUP00000001877	ENSSDUP00000014331	Uncharacterized protein.	Claudin 11a.	0.668
ENSSDUP00000001877	LOC111231759	ENSSDUP00000001877	ENSSDUP00000018346	Uncharacterized protein.	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	0.658
ENSSDUP00000001877	LOC111239310	ENSSDUP00000001877	ENSSDUP00000028642	Uncharacterized protein.	Claudin 23a.	0.659
ENSSDUP00000001877	cldn11	ENSSDUP00000001877	ENSSDUP00000004403	Uncharacterized protein.	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	0.668

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Network Stats

number of nodes:

11

number of edges:

32

average node degree:

5.82

avg. local clustering coefficient:

0.839

expected number of edges:

12

PPI enrichment p-value:

7.43e-07

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0006412

Translation

11 of 95

1.49

3.06

7.72e-14

GO:0002181

Cytoplasmic translation

2 of 3

2.25

1.21

0.0056

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0019843

rRNA binding

11 of 40

1.86

5.42

6.72e-18

GO:0003735

Structural constituent of ribosome

11 of 49

1.78

4.85

2.42e-17

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0022626

Cytosolic ribosome

11 of 31

1.98

6.36

1.43e-19

GO:0022625

Cytosolic large ribosomal subunit

9 of 20

2.08

6.09

2.83e-16

GO:0044391

Ribosomal subunit

11 of 40

1.86

5.58

7.93e-19

GO:0022627

Cytosolic small ribosomal subunit

2 of 11

1.69

1.03

0.0076

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:106

rRNA-binding

11 of 28

2.02

6.54

3.15e-19

CL:135

Cytosolic large ribosomal subunit

8 of 12

2.25

6.21

9.89e-15

CL:137

Cytosolic large ribosomal subunit

3 of 5

2.2

2.1

8.39e-05

CL:110

Cytosolic small ribosomal subunit, and Ribosomal protein S13-like, H2TH

2 of 8

1.82

0.87

0.0207

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

pbas03010

Ribosome

11 of 51

1.76

4.8

1.39e-17

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0044391

Ribosomal subunit

7 of 15

2.09

4.59

3.18e-11

GOCC:0015934

Large ribosomal subunit

5 of 6

2.35

4.16

4.16e-09

GOCC:0005840

Ribosome

8 of 36

1.77

3.71

3.18e-11

GOCC:0022626

Cytosolic ribosome

5 of 10

2.12

3.61

2.01e-08

GOCC:0022625

Cytosolic large ribosomal subunit

3 of 3

2.43

2.52

1.67e-05

(more ...)

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0699

rRNA-binding

11 of 37

1.9

5.75

1.16e-18

KW-0689

Ribosomal protein

11 of 52

1.75

4.74

1.58e-17

KW-0820

tRNA-binding

2 of 11

1.69

0.74

0.0349

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