LOC111237528 protein (Seriola dumerili) - STRING interaction network

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Known Interactions

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Predicted Interactions

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Score

LOC111237528

Lecithin retinol acyltransferase b, tandem duplicate 1. (307 aa)

Predicted Functional Partners:

LOC111237093

0.926

LOC111223679

0.924

LOC111220358

0.924

retsat

0.924

LOC111223483

0.918

rpe65

0.918

sdr16c5

0.917

dhrs3

0.917

LOC111235588

0.905

LOC111238623

0.902

Your Current Organism:

Seriola dumerili

NCBI taxonomy Id: 41447
Other names: S. dumerili, greater amberjack

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC111220358	LOC111223679	ENSSDUP00000017529	ENSSDUP00000008953	Si:ch1073-13h15.3.	Amino_oxidase domain-containing protein.	0.901
LOC111220358	LOC111235588	ENSSDUP00000017529	ENSSDUP00000008856	Si:ch1073-13h15.3.	Dehydrogenase/reductase (SDR family) member 4.	0.916
LOC111220358	LOC111237093	ENSSDUP00000017529	ENSSDUP00000022870	Si:ch1073-13h15.3.	Cytochrome P450, family 26, subfamily A, polypeptide 1; Belongs to the cytochrome P450 family.	0.910
LOC111220358	LOC111237528	ENSSDUP00000017529	ENSSDUP00000028646	Si:ch1073-13h15.3.	Lecithin retinol acyltransferase b, tandem duplicate 1.	0.924
LOC111220358	LOC111238623	ENSSDUP00000017529	ENSSDUP00000029433	Si:ch1073-13h15.3.	Cytochrome P450, family 27, subfamily C, polypeptide 1; Belongs to the cytochrome P450 family.	0.907
LOC111220358	dhrs3	ENSSDUP00000017529	ENSSDUP00000024673	Si:ch1073-13h15.3.	Dehydrogenase/reductase (SDR family) member 3b; Belongs to the short-chain dehydrogenases/reductases (SDR) family.	0.922
LOC111220358	retsat	ENSSDUP00000017529	ENSSDUP00000031306	Si:ch1073-13h15.3.	Retinol saturase (all-trans-retinol 13,14-reductase).	0.903
LOC111220358	sdr16c5	ENSSDUP00000017529	ENSSDUP00000005761	Si:ch1073-13h15.3.	Short chain dehydrogenase/reductase family 16C, member 5a; Belongs to the short-chain dehydrogenases/reductases (SDR) family.	0.912
LOC111223483	LOC111237528	ENSSDUP00000023336	ENSSDUP00000028646	Retinoid isomerohydrolase RPE65 b.	Lecithin retinol acyltransferase b, tandem duplicate 1.	0.918
LOC111223483	rpe65	ENSSDUP00000023336	ENSSDUP00000025818	Retinoid isomerohydrolase RPE65 b.	Retinoid isomerohydrolase RPE65 a.	0.901
LOC111223679	LOC111220358	ENSSDUP00000008953	ENSSDUP00000017529	Amino_oxidase domain-containing protein.	Si:ch1073-13h15.3.	0.901
LOC111223679	LOC111235588	ENSSDUP00000008953	ENSSDUP00000008856	Amino_oxidase domain-containing protein.	Dehydrogenase/reductase (SDR family) member 4.	0.916
LOC111223679	LOC111237093	ENSSDUP00000008953	ENSSDUP00000022870	Amino_oxidase domain-containing protein.	Cytochrome P450, family 26, subfamily A, polypeptide 1; Belongs to the cytochrome P450 family.	0.910
LOC111223679	LOC111237528	ENSSDUP00000008953	ENSSDUP00000028646	Amino_oxidase domain-containing protein.	Lecithin retinol acyltransferase b, tandem duplicate 1.	0.924
LOC111223679	LOC111238623	ENSSDUP00000008953	ENSSDUP00000029433	Amino_oxidase domain-containing protein.	Cytochrome P450, family 27, subfamily C, polypeptide 1; Belongs to the cytochrome P450 family.	0.907
LOC111223679	dhrs3	ENSSDUP00000008953	ENSSDUP00000024673	Amino_oxidase domain-containing protein.	Dehydrogenase/reductase (SDR family) member 3b; Belongs to the short-chain dehydrogenases/reductases (SDR) family.	0.922
LOC111223679	retsat	ENSSDUP00000008953	ENSSDUP00000031306	Amino_oxidase domain-containing protein.	Retinol saturase (all-trans-retinol 13,14-reductase).	0.902
LOC111223679	sdr16c5	ENSSDUP00000008953	ENSSDUP00000005761	Amino_oxidase domain-containing protein.	Short chain dehydrogenase/reductase family 16C, member 5a; Belongs to the short-chain dehydrogenases/reductases (SDR) family.	0.912
LOC111235588	LOC111220358	ENSSDUP00000008856	ENSSDUP00000017529	Dehydrogenase/reductase (SDR family) member 4.	Si:ch1073-13h15.3.	0.916
LOC111235588	LOC111223679	ENSSDUP00000008856	ENSSDUP00000008953	Dehydrogenase/reductase (SDR family) member 4.	Amino_oxidase domain-containing protein.	0.916

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Network Stats

number of nodes:

11

number of edges:

39

average node degree:

7.09

avg. local clustering coefficient:

0.968

expected number of edges:

43

PPI enrichment p-value:

0.736

your network does not have significantly more
interactions than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
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Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0030176

Integral component of endoplasmic reticulum membrane

3 of 132

1.63

0.79

0.0265

GO:0005615

Extracellular space

6 of 1087

1.02

0.69

0.0095

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:4709

Mixed, incl. Lipolysis stimulated receptor (LSR), and Kringle

6 of 10

3.05

6.91

1.44e-13

CL:4713

Kringle, and Establishment of epithelial cell apical/basal polarity

4 of 5

3.18

4.72

2.48e-09

CL:4690

Immunoglobulin C-2 Type, and Leucine rich repeat N-terminal domain

7 of 143

1.97

4.0

2.48e-10

CL:4409

MHC I, and MHC class I-like antigen recognition-like superfamily

2 of 6

2.8

1.44

0.0024

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0420

Kringle

3 of 19

2.47

2.27

5.53e-05

KW-0720

Serine protease

3 of 80

1.85

1.38

0.0016

KW-1015

Disulfide bond

6 of 1146

1.0

0.81

0.0016

KW-0245

EGF-like domain

3 of 226

1.4

0.8

0.0167

KW-0964

Secreted

3 of 242

1.37

0.79

0.0167

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR038178

Kringle superfamily

3 of 19

2.47

1.77

0.00052

IPR000001

Kringle

3 of 19

2.47

1.77

0.00052

IPR013806

Kringle-like fold

3 of 28

2.31

1.74

0.00052

IPR003591

Leucine-rich repeat, typical subtype

5 of 199

1.68

1.6

0.00026

IPR001611

Leucine-rich repeat

5 of 270

1.54

1.4

0.00052

(more ...)

Protein Domains (SMART)

domain

description

count in network

strength

signal

false discovery rate

SM00130

Kringle domain

3 of 19

2.47

2.24

6.46e-05

SM00013

Leucine rich repeat N-terminal domain

4 of 117

1.81

1.88

8.90e-05

SM00370

Leucine-rich repeats, outliers

5 of 233

1.61

1.75

6.30e-05

SM00369

Leucine-rich repeats, typical (most populated) subfamily

4 of 160

1.67

1.62

0.00023

SM00020

Trypsin-like serine protease

3 of 97

1.77

1.25

0.0027

(more ...)

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