STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
dlx2Distal-less homeobox 2b. (276 aa)    
Predicted Functional Partners:
dlx1
Distal-less homeobox 1a.
   
 
0.806
bmp4
Bone morphogenetic protein 4.
     
 0.573
rag2
Recombination activating gene 2.
      
 0.559
rag1
V(D)J recombination-activating protein 1; Catalytic component of the RAG complex, a multiprotein complex that mediates the DNA cleavage phase during V(D)J recombination. V(D)J recombination assembles a diverse repertoire of immunoglobulin and T-cell receptor genes in developing B and T- lymphocytes through rearrangement of different V (variable), in some cases D (diversity), and J (joining) gene segments. In the RAG complex, RAG1 mediates the DNA-binding to the conserved recombination signal sequences (RSS) and catalyzes the DNA cleavage activities by introducing a double-strand break [...]
      
 0.538
ENSSDUP00000030445
Uncharacterized protein.
      
 0.534
lef1
Lymphoid enhancer-binding factor 1.
    
 0.516
LOC111230313
Parvalbumin 6; Belongs to the parvalbumin family.
      
 0.515
sox10
SRY-box transcription factor 10.
    
 
 0.491
hand2
Heart and neural crest derivatives expressed 2.
      
 0.475
irx2
Iroquois homeobox 2a.
   
 
 0.475
Your Current Organism:
Seriola dumerili
NCBI taxonomy Id: 41447
Other names: S. dumerili, greater amberjack
Server load: medium (62%) [ZH]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.