kit protein (Seriola dumerili) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

kit

Uncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (986 aa)

Predicted Functional Partners:

kitlg

0.988

hras

0.935

LOC111230220

0.934

kras

0.934

grb2

0.907

LOC111231521

0.901

il34

0.880

LOC111216519

0.797

ENSSDUP00000009359

0.789

LOC111217308

0.789

Your Current Organism:

Seriola dumerili

NCBI taxonomy Id: 41447
Other names: S. dumerili, greater amberjack

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSSDUP00000009359	LOC111231521	ENSSDUP00000009359	ENSSDUP00000005537	Uncharacterized protein.	KIT proto-oncogene, receptor tyrosine kinase b; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.	0.789
ENSSDUP00000009359	il34	ENSSDUP00000009359	ENSSDUP00000029568	Uncharacterized protein.	Interleukin 34.	0.825
ENSSDUP00000009359	kit	ENSSDUP00000009359	ENSSDUP00000031897	Uncharacterized protein.	Uncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.	0.789
LOC111216519	LOC111231521	ENSSDUP00000018222	ENSSDUP00000005537	Platelet-derived growth factor beta polypeptide a; Belongs to the PDGF/VEGF growth factor family.	KIT proto-oncogene, receptor tyrosine kinase b; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.	0.797
LOC111216519	grb2	ENSSDUP00000018222	ENSSDUP00000024464	Platelet-derived growth factor beta polypeptide a; Belongs to the PDGF/VEGF growth factor family.	Growth factor receptor-bound protein 2b.	0.409
LOC111216519	kit	ENSSDUP00000018222	ENSSDUP00000031897	Platelet-derived growth factor beta polypeptide a; Belongs to the PDGF/VEGF growth factor family.	Uncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.	0.797
LOC111217308	LOC111231521	ENSSDUP00000019857	ENSSDUP00000005537	Colony stimulating factor 1b (macrophage).	KIT proto-oncogene, receptor tyrosine kinase b; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.	0.789
LOC111217308	il34	ENSSDUP00000019857	ENSSDUP00000029568	Colony stimulating factor 1b (macrophage).	Interleukin 34.	0.825
LOC111217308	kit	ENSSDUP00000019857	ENSSDUP00000031897	Colony stimulating factor 1b (macrophage).	Uncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.	0.789
LOC111217308	kitlg	ENSSDUP00000019857	ENSSDUP00000006714	Colony stimulating factor 1b (macrophage).	Kit ligand a.	0.457
LOC111230220	LOC111231521	ENSSDUP00000023610	ENSSDUP00000005537	Zgc:55558.	KIT proto-oncogene, receptor tyrosine kinase b; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.	0.934
LOC111230220	grb2	ENSSDUP00000023610	ENSSDUP00000024464	Zgc:55558.	Growth factor receptor-bound protein 2b.	0.697
LOC111230220	hras	ENSSDUP00000023610	ENSSDUP00000026309	Zgc:55558.	HRas proto-oncogene, GTPase a.	0.910
LOC111230220	kit	ENSSDUP00000023610	ENSSDUP00000031897	Zgc:55558.	Uncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.	0.934
LOC111230220	kitlg	ENSSDUP00000023610	ENSSDUP00000006714	Zgc:55558.	Kit ligand a.	0.438
LOC111230220	kras	ENSSDUP00000023610	ENSSDUP00000024473	Zgc:55558.	V-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog.	0.901
LOC111231521	ENSSDUP00000009359	ENSSDUP00000005537	ENSSDUP00000009359	KIT proto-oncogene, receptor tyrosine kinase b; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.	Uncharacterized protein.	0.789
LOC111231521	LOC111216519	ENSSDUP00000005537	ENSSDUP00000018222	KIT proto-oncogene, receptor tyrosine kinase b; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.	Platelet-derived growth factor beta polypeptide a; Belongs to the PDGF/VEGF growth factor family.	0.797
LOC111231521	LOC111217308	ENSSDUP00000005537	ENSSDUP00000019857	KIT proto-oncogene, receptor tyrosine kinase b; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.	Colony stimulating factor 1b (macrophage).	0.789
LOC111231521	LOC111230220	ENSSDUP00000005537	ENSSDUP00000023610	KIT proto-oncogene, receptor tyrosine kinase b; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.	Zgc:55558.	0.934