STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mto1Mitochondrial tRNA translation optimization 1. (685 aa)    
Predicted Functional Partners:
gtpbp3
GTP binding protein 3, mitochondrial; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
 0.988
trmu
tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase.
  
 0.904
vps45
Vacuolar protein sorting 45 homolog; Belongs to the STXBP/unc-18/SEC1 family.
 
      0.900
cars2
Cysteinyl-tRNA synthetase 2, mitochondrial.
  
  
 0.687
supt7l
SPT7 like, STAGA complex gamma subunit.
   
  
 0.686
mtfmt
Mitochondrial methionyl-tRNA formyltransferase.
  
  
 0.655
yars1
Tyrosine--tRNA ligase.
  
  
 0.631
pus1
Pseudouridine synthase 1.
  
  
 0.600
mocs3
Adenylyltransferase and sulfurtransferase MOCS3; Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Also essential during biosynthesis of the molybdenum cofactor. Acts by mediating the C-terminal thiocarboxylation of sulfur carriers URM1 and MOCS2A. Its N-terminus first activates URM1 and MOCS2A as acyl- adenylates (-COAMP), then the persulfide sulfur on the catalytic cysteine is transferred to URM1 and MOCS2A to form thiocarboxylation (- COSH) of their C-terminus. The reaction probably involves hydrogen sulfide [...]
   
  
 0.597
Fam104a
Uncharacterized protein.
      
 0.596
Your Current Organism:
Seriola dumerili
NCBI taxonomy Id: 41447
Other names: S. dumerili, greater amberjack
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.