| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| RC1_0779 | cbs | RC1_0779 | RC1_1987 | Threonine dehydratase, putative; Synonym identified by match to protein family HMM PF00483. | Cystathionine beta-synthase; Identified by match to protein family HMM PF02491 match to protein family HMM PF06723 match to protein family HMM TIGR00904. | 0.932 |
| RC1_0779 | glyA | RC1_0779 | RC1_1342 | Threonine dehydratase, putative; Synonym identified by match to protein family HMM PF00483. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.918 |
| RC1_0779 | ilvA | RC1_0779 | RC1_3167 | Threonine dehydratase, putative; Synonym identified by match to protein family HMM PF00483. | Threonine dehydratase; Identified by match to protein family HMM PF00830 match to protein family HMM TIGR00009. | 0.923 |
| RC1_0779 | pssA | RC1_0779 | RC1_1431 | Threonine dehydratase, putative; Synonym identified by match to protein family HMM PF00483. | CDP-diacylglycerol--serine O-phosphatidyltransferase; [synonyms] Phosphatidylserine synt Hase identified by match to protein family HMM PF01058; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | 0.900 |
| RC1_0779 | serB | RC1_0779 | RC1_1979 | Threonine dehydratase, putative; Synonym identified by match to protein family HMM PF00483. | Phosphoserine phosphatase. | 0.911 |
| RC1_1549 | cdsA | RC1_1549 | RC1_1203 | CDP-alcohol phosphatidyltransferase, putative; Identified by match to protein family HMM PF00595 match to protein family HMM PF03572 match to protein family HMM TIGR00225; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | Phosphatidate cytidylyltransferase; Identified by match to protein family HMM PF03772 match to protein family HMM TIGR00360; Belongs to the CDS family. | 0.936 |
| RC1_1549 | pcs | RC1_1549 | RC1_1051 | CDP-alcohol phosphatidyltransferase, putative; Identified by match to protein family HMM PF00595 match to protein family HMM PF03572 match to protein family HMM TIGR00225; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | Phosphatidylcholine synthase; Condenses choline with CDP-diglyceride to produce phosphatidylcholine and CMP; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | 0.920 |
| RC1_1549 | pgsA | RC1_1549 | RC1_1886 | CDP-alcohol phosphatidyltransferase, putative; Identified by match to protein family HMM PF00595 match to protein family HMM PF03572 match to protein family HMM TIGR00225; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | 0.923 |
| RC1_1549 | pssA | RC1_1549 | RC1_1431 | CDP-alcohol phosphatidyltransferase, putative; Identified by match to protein family HMM PF00595 match to protein family HMM PF03572 match to protein family HMM TIGR00225; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | CDP-diacylglycerol--serine O-phosphatidyltransferase; [synonyms] Phosphatidylserine synt Hase identified by match to protein family HMM PF01058; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | 0.935 |
| cbs | RC1_0779 | RC1_1987 | RC1_0779 | Cystathionine beta-synthase; Identified by match to protein family HMM PF02491 match to protein family HMM PF06723 match to protein family HMM TIGR00904. | Threonine dehydratase, putative; Synonym identified by match to protein family HMM PF00483. | 0.932 |
| cbs | glyA | RC1_1987 | RC1_1342 | Cystathionine beta-synthase; Identified by match to protein family HMM PF02491 match to protein family HMM PF06723 match to protein family HMM TIGR00904. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.953 |
| cbs | ilvA | RC1_1987 | RC1_3167 | Cystathionine beta-synthase; Identified by match to protein family HMM PF02491 match to protein family HMM PF06723 match to protein family HMM TIGR00904. | Threonine dehydratase; Identified by match to protein family HMM PF00830 match to protein family HMM TIGR00009. | 0.955 |
| cbs | pssA | RC1_1987 | RC1_1431 | Cystathionine beta-synthase; Identified by match to protein family HMM PF02491 match to protein family HMM PF06723 match to protein family HMM TIGR00904. | CDP-diacylglycerol--serine O-phosphatidyltransferase; [synonyms] Phosphatidylserine synt Hase identified by match to protein family HMM PF01058; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | 0.901 |
| cbs | serB | RC1_1987 | RC1_1979 | Cystathionine beta-synthase; Identified by match to protein family HMM PF02491 match to protein family HMM PF06723 match to protein family HMM TIGR00904. | Phosphoserine phosphatase. | 0.938 |
| cdsA | RC1_1549 | RC1_1203 | RC1_1549 | Phosphatidate cytidylyltransferase; Identified by match to protein family HMM PF03772 match to protein family HMM TIGR00360; Belongs to the CDS family. | CDP-alcohol phosphatidyltransferase, putative; Identified by match to protein family HMM PF00595 match to protein family HMM PF03572 match to protein family HMM TIGR00225; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | 0.936 |
| cdsA | pcs | RC1_1203 | RC1_1051 | Phosphatidate cytidylyltransferase; Identified by match to protein family HMM PF03772 match to protein family HMM TIGR00360; Belongs to the CDS family. | Phosphatidylcholine synthase; Condenses choline with CDP-diglyceride to produce phosphatidylcholine and CMP; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | 0.926 |
| cdsA | pgsA | RC1_1203 | RC1_1886 | Phosphatidate cytidylyltransferase; Identified by match to protein family HMM PF03772 match to protein family HMM TIGR00360; Belongs to the CDS family. | CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | 0.938 |
| cdsA | pssA | RC1_1203 | RC1_1431 | Phosphatidate cytidylyltransferase; Identified by match to protein family HMM PF03772 match to protein family HMM TIGR00360; Belongs to the CDS family. | CDP-diacylglycerol--serine O-phosphatidyltransferase; [synonyms] Phosphatidylserine synt Hase identified by match to protein family HMM PF01058; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | 0.927 |
| glyA | RC1_0779 | RC1_1342 | RC1_0779 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Threonine dehydratase, putative; Synonym identified by match to protein family HMM PF00483. | 0.918 |
| glyA | cbs | RC1_1342 | RC1_1987 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Cystathionine beta-synthase; Identified by match to protein family HMM PF02491 match to protein family HMM PF06723 match to protein family HMM TIGR00904. | 0.953 |