STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pepNAminopeptidase N, PepN, putative; TIGR02414 PF01433: Peptidase family M1; The M1 family of zinc metallopeptidases contains a number of distinct, well-separated clades of proteins With aminopeptidase activity; identified by match to protein family HMM PF04545 match to protein family HMM TIGR02937. (890 aa)    
Predicted Functional Partners:
pepA
Leucyl aminopeptidase PepA, putative; Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N- terminal amino acids from various peptides.
   
 0.927
pepB
Leucyl aminopeptidase PepB, putative; In a close position to genes from the similar family; With a good score above the trusted cutoff and uncharacterized homologs; SP|P37095| Peptidase B (EC 3.4.11.23) (Aminopeptidase B); identified by match to protein family HMM PF04389.
   
 0.927
gshB
Glutathione synthase; Belongs to the prokaryotic GSH synthase family.
    
 0.919
ggt
Gamma-glutamyltransferase; Identified by match to protein family HMM PF00355.
     
 0.909
ggt-2
Gamma-glutamyltransferase; Identified by match to protein family HMM PF07486.
     
 0.909
gshA
Glutamate--cysteine ligase; Catalyzes the synthesis of gamma-glutamylcysteine (gamma-GC). Belongs to the glutamate--cysteine ligase type 2 family. EgtA subfamily.
     
  0.900
chaC
Cation transport protein ChaC, putative; Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides; Belongs to the gamma-glutamylcyclotransferase family.
    
  0.900
glyA
Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
    
 0.846
cysK
Cysteine synthase A; O-acetylserine sulfhydrylase,O-acetylserine (Thiol)-lyase identified by match to protein family HMM PF01578 match to protein family HMM TIGR00353.
   
 0.834
metC
Cystathionine beta-lyase.
    
 0.803
Your Current Organism:
Rhodospirillum centenum
NCBI taxonomy Id: 414684
Other names: R. centenum SW, Rhodocista centenaria SW, Rhodospirillum centenum SW, Rhodospirillum centenum str. SW, Rhodospirillum centenum strain SW
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