Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
mrdAPenicillin-binding protein 2; Gene symbol synonym pbpA.Part of the rodA operon. (643 aa)    
Predicted Functional Partners:
rodA
Rod shape-determining protein RodA (FtsW, Bacterial cell division membrane protein); Peptidoglycan polymerase that is essential for cell wall elongation; Belongs to the SEDS family. MrdB/RodA subfamily.
 
 0.997
mreC
Rod shape-determining protein MreC, putative; Involved in formation and maintenance of cell shape.
 
 
 0.989
mtgA
Monofunctional biosynthetic peptidoglycan transglycosylase, putative; Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors; Belongs to the glycosyltransferase 51 family.
 
 
 0.978
RC1_2700
Penicillin-binding protein, 1A family; TIGR02074 With a good score above the trusted cutoff and uncharacterized homologs; PF00905: Penicillin binding protein transpeptidase domain.
 
 
0.974
mrcA
Penicillin-binding protein 1A (PBP-1a) (PBP1a) MrcA, putative; TIGR02074 PF00905: Penicillin binding protein transpeptidase domain; Penicillin-insensitive transglycosylase (EC 2.4.2.-)(Peptidoglycan TGase) Penicillin-sensitive transpeptidase(EC 3.4.-.-)(DD-transpeptidase); identified by match to protein family HMM PF00070 match to protein family HMM PF02852 match to protein family HMM PF07992 match to protein family HMM TIGR01424.
 
 
 0.971
mreB
Rod shape-determining protein MreB (actin-like ATPase domain); Gene symbol synonyms envB rodY; identified by match to protein family HMM PF00378 match to protein family HMM PF00725 match to protein family HMM PF02737.
 
 
 
 0.947
dacA
D-alanyl-D-alanine carboxypeptidase; Also called penicillin-binding protein 5.Gene symbol synonym PFv; Belongs to the peptidase S11 family.
 
 
 0.945
ftsI
Peptidoglycan synthetase FtsI; Gene symbol synonym pbpB.Also called penicillin-binding protein 3; identified by match to protein family HMM PF01225 match to protein family HMM PF02875 match to protein family HMM TIGR01082.
  
  
0.932
ftsW
Cell division protein FtsW, putative; Identified by match to protein family HMM PF02491 match to protein family HMM TIGR01174; Belongs to the SEDS family.
 
 0.925
mreD
Rod shape-determining protein MreD, putative.
 
  
 0.920
Your Current Organism:
Rhodospirillum centenum
NCBI taxonomy Id: 414684
Other names: R. centenum SW, Rhodocista centenaria SW, Rhodospirillum centenum SW, Rhodospirillum centenum str. SW, Rhodospirillum centenum strain SW
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