Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
hflCHflC protein, putative; HflC and HflK could regulate a protease. (307 aa)    
Predicted Functional Partners:
hflK
HflK protein, putative; HflC and HflK could encode or regulate a protease.
 
 
0.995
ftsH
ATP-dependent metalloprotease FtsH; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family.
  
 0.924
RC1_0046
Conserved hypothetical protein.
    
 0.693
engB
GTP-binding protein, putative; Necessary for normal cell division and for the maintenance of normal septation; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
  
    0.676
yidC
Conserved hypothetical protein; Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.
 
 
 0.664
RC1_2900
Low molecular weight phosphotyrosine protein phosphatase, putative; Identified by match to protein family HMM PF00763 match to protein family HMM PF02882; Belongs to the low molecular weight phosphotyrosine protein phosphatase family.
  
    0.663
coxB
Cytochrome c oxidase subunit II (Heme/copper-type cytochrome/quinol oxidase); Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B).
   
   0.657
ctaC
Cytochrome c oxidase, subunit II (Heme/copper-type cytochrome/quinol oxidases); Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B).
   
   0.657
nfeD
Nodulation efficiency protein D, putative; Identified by match to protein family HMM PF01739 match to protein family HMM PF03705.
 
 
 0.648
RC1_3589
Peptidase M16, putative; PF05193 With a good score above the trusted cutoff and uncharacterized homologs; identified by match to protein family HMM PF01590 match to protein family HMM PF07721.
  
 0.627
Your Current Organism:
Rhodospirillum centenum
NCBI taxonomy Id: 414684
Other names: R. centenum SW, Rhodocista centenaria SW, Rhodospirillum centenum SW, Rhodospirillum centenum str. SW, Rhodospirillum centenum strain SW
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