Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
Experiments
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[Homology]
Score
cbsCystathionine beta-synthase; Identified by match to protein family HMM PF02491 match to protein family HMM PF06723 match to protein family HMM TIGR00904. (461 aa)    
Predicted Functional Partners:
RC1_1986
Cystathionine gamma-synthase (CGS) (O-succinylhomoserine(Thiol)-lyase); Identified by match to protein family HMM PF04085 match to protein family HMM TIGR00219.
 
 0.997
RC1_0523
Cys.
 
 0.991
metC
Cystathionine beta-lyase.
 
 0.989
metZ
O-succinylhomoserine sulfhydrylase; Catalyzes the formation of L-homocysteine from O-succinyl-L- homoserine (OSHS) and hydrogen sulfide.
 
 0.989
RC1_1319
O-acetylhomoserine sulfhydrylase; Identified by match to protein family HMM PF00742 match to protein family HMM PF01408 match to protein family HMM PF01842 match to protein family HMM PF03447.
 
 0.988
cysE-2
Serine acetyltransferase; Identified by match to protein family HMM PF01077 match to protein family HMM PF03460.
 
 0.971
cysE
Serine O-acetyltransferase; Identified by match to protein family HMM PF02586.
 
 0.970
glyA
Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
  
 
 0.951
cysNC
Bifunctional enzyme cysN; Catalyzes the synthesis of activated sulfate. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.
  
  
 0.950
ahcY
Adenosylhomocysteinase, putative; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.
  
 0.949
Your Current Organism:
Rhodospirillum centenum
NCBI taxonomy Id: 414684
Other names: R. centenum SW, Rhodocista centenaria SW, Rhodospirillum centenum SW, Rhodospirillum centenum str. SW, Rhodospirillum centenum strain SW
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