| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| RC1_2169 | dnaB | RC1_2169 | RC1_1577 | RNA polymerase sigma-32 factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | Replicative DNA helicase, putative; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. Belongs to the helicase family. DnaB subfamily. | 0.608 |
| RC1_2169 | dnaE | RC1_2169 | RC1_1210 | RNA polymerase sigma-32 factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | DNA polymerase III alpha subunit; Identified by match to protein family HMM PF07977 match to protein family HMM TIGR01750. | 0.558 |
| RC1_2169 | dnaG | RC1_2169 | RC1_2007 | RNA polymerase sigma-32 factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | DNA primase, catalytic core, putative; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. | 0.841 |
| RC1_2169 | guaB | RC1_2169 | RC1_0155 | RNA polymerase sigma-32 factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.453 |
| RC1_2169 | rpoD | RC1_2169 | RC1_2006 | RNA polymerase sigma-32 factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | DNA-directed RNA polymerase, sigma subunit RpoD; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth. | 0.543 |
| der | dnaG | RC1_1401 | RC1_2007 | GTP-binding protein, putative; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family. | DNA primase, catalytic core, putative; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. | 0.933 |
| der | guaB | RC1_1401 | RC1_0155 | GTP-binding protein, putative; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.593 |
| dnaB | RC1_2169 | RC1_1577 | RC1_2169 | Replicative DNA helicase, putative; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. Belongs to the helicase family. DnaB subfamily. | RNA polymerase sigma-32 factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | 0.608 |
| dnaB | dnaE | RC1_1577 | RC1_1210 | Replicative DNA helicase, putative; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. Belongs to the helicase family. DnaB subfamily. | DNA polymerase III alpha subunit; Identified by match to protein family HMM PF07977 match to protein family HMM TIGR01750. | 0.697 |
| dnaB | dnaG | RC1_1577 | RC1_2007 | Replicative DNA helicase, putative; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. Belongs to the helicase family. DnaB subfamily. | DNA primase, catalytic core, putative; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. | 0.986 |
| dnaB | recG | RC1_1577 | RC1_1265 | Replicative DNA helicase, putative; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. Belongs to the helicase family. DnaB subfamily. | ATP-dependent DNA helicase RecG; Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y- DNA); Belongs to the helicase family. RecG subfamily. | 0.533 |
| dnaB | rpoD | RC1_1577 | RC1_2006 | Replicative DNA helicase, putative; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. Belongs to the helicase family. DnaB subfamily. | DNA-directed RNA polymerase, sigma subunit RpoD; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth. | 0.472 |
| dnaB | rpoH-2 | RC1_1577 | RC1_2225 | Replicative DNA helicase, putative; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. Belongs to the helicase family. DnaB subfamily. | RNA polymerase sigma-32 factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | 0.520 |
| dnaE | RC1_2169 | RC1_1210 | RC1_2169 | DNA polymerase III alpha subunit; Identified by match to protein family HMM PF07977 match to protein family HMM TIGR01750. | RNA polymerase sigma-32 factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | 0.558 |
| dnaE | dnaB | RC1_1210 | RC1_1577 | DNA polymerase III alpha subunit; Identified by match to protein family HMM PF07977 match to protein family HMM TIGR01750. | Replicative DNA helicase, putative; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. Belongs to the helicase family. DnaB subfamily. | 0.697 |
| dnaE | dnaG | RC1_1210 | RC1_2007 | DNA polymerase III alpha subunit; Identified by match to protein family HMM PF07977 match to protein family HMM TIGR01750. | DNA primase, catalytic core, putative; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. | 0.827 |
| dnaE | guaB | RC1_1210 | RC1_0155 | DNA polymerase III alpha subunit; Identified by match to protein family HMM PF07977 match to protein family HMM TIGR01750. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.439 |
| dnaE | recG | RC1_1210 | RC1_1265 | DNA polymerase III alpha subunit; Identified by match to protein family HMM PF07977 match to protein family HMM TIGR01750. | ATP-dependent DNA helicase RecG; Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y- DNA); Belongs to the helicase family. RecG subfamily. | 0.466 |
| dnaE | rpoD | RC1_1210 | RC1_2006 | DNA polymerase III alpha subunit; Identified by match to protein family HMM PF07977 match to protein family HMM TIGR01750. | DNA-directed RNA polymerase, sigma subunit RpoD; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth. | 0.498 |
| dnaE | rpoH-2 | RC1_1210 | RC1_2225 | DNA polymerase III alpha subunit; Identified by match to protein family HMM PF07977 match to protein family HMM TIGR01750. | RNA polymerase sigma-32 factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | 0.474 |