Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ttuDHydroxypyruvate reductase, putative; [contains] MOFRL domain identified by match to protein family HMM PF07284 match to protein family HMM TIGR02020. (429 aa)    
Predicted Functional Partners:
gyaR
Glyoxylate reductase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
 
 0.958
pyk
Pyruvate kinase; Identified by match to protein family HMM PF00148 match to protein family HMM TIGR01279; Belongs to the pyruvate kinase family.
 
 
 0.938
eno
Phosphopyruvate hydratase, putative; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family.
    
 0.929
RC1_3398
2-hydroxyacid dehydrogenase; Identified by match to protein family HMM PF00005 match to protein family HMM TIGR01727.
    
 0.913
betB
Betaine aldehyde dehydrogenase; Identified by match to protein family HMM PF00464 match to protein family HMM PF01212; Belongs to the aldehyde dehydrogenase family.
     
 0.902
gpmA
Phosphoglycerate mutase 1 family; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily.
     
 0.901
RC1_2401
Pyruvate kinase; Belongs to the pyruvate kinase family.
  
 
 0.845
RC1_3506
L-lactate dehydrogenase; Catalyzes the conversion of lactate to pyruvate.
    
 0.838
pgi
Glucose-6-phosphate isomerase; Identified by match to protein family HMM PF00391 match to protein family HMM PF01326 match to protein family HMM PF02896 match to protein family HMM TIGR01418; Belongs to the GPI family.
    
 0.821
ppdK
[synonyms] pyruvate, orthophosphate dikinase identified by match to protein family HMM PF01451; Belongs to the PEP-utilizing enzyme family.
    
  0.820
Your Current Organism:
Rhodospirillum centenum
NCBI taxonomy Id: 414684
Other names: R. centenum SW, Rhodocista centenaria SW, Rhodospirillum centenum SW, Rhodospirillum centenum str. SW, Rhodospirillum centenum strain SW
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