STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
acsAAcetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (646 aa)    
Predicted Functional Partners:
gltA
Citrate synthase I; Both chromosomal and plasmid encoded identified by match to protein family HMM PF00015 match to protein family HMM PF00672; Belongs to the citrate synthase family.
  
 0.976
prpC
2-methylcitrate synthase; [synonyms] Citrate synt Hase II; Belongs to the citrate synthase family.
  
 0.976
aceB
Malate synthase A; Identified by match to protein family HMM PF00639; Belongs to the malate synthase family.
   
 0.972
fadJ
Fatty acid oxidation complex alpha subunit; [includes] Enoyl-CoA hydratase 3-hydroxyacyl-CoA dehydrogenase 3-hydroxybutyryl-CoA epimerase identified by match to protein family HMM PF04542 match to protein family HMM PF04545 match to protein family HMM TIGR02392 match to protein family HMM TIGR02937.
 
 0.958
betB
Betaine aldehyde dehydrogenase; Identified by match to protein family HMM PF00464 match to protein family HMM PF01212; Belongs to the aldehyde dehydrogenase family.
  
 0.945
RC1_0397
acetyl-CoA acetyltransferase; Identified by match to protein family HMM PF00487; Belongs to the thiolase-like superfamily. Thiolase family.
  
 
 0.944
fadA
3-ketoacyl-CoA thiolase; [synonym] (Fatty oxidation complex beta subunit); Belongs to the thiolase-like superfamily. Thiolase family.
  
 
 0.944
RC1_3948
acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.
  
 
 0.944
RC1_0310
succinyl-CoA transferase.
  
 0.943
accC
acetyl-CoA carboxylase, biotin carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.
  
 0.932
Your Current Organism:
Rhodospirillum centenum
NCBI taxonomy Id: 414684
Other names: R. centenum SW, Rhodocista centenaria SW, Rhodospirillum centenum SW, Rhodospirillum centenum str. SW, Rhodospirillum centenum strain SW
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