| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| RC1_1904 | RC1_2548 | RC1_1904 | RC1_2548 | Conserved hypothetical protein; Belongs to the multicopper oxidase YfiH/RL5 family. | Conserved hypothetical protein; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family. | 0.869 |
| RC1_2547 | RC1_2548 | RC1_2547 | RC1_2548 | HIT family proteinspeci; Identified by match to protein family HMM PF00571 match to protein family HMM PF01595 match to protein family HMM PF03471. | Conserved hypothetical protein; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family. | 0.601 |
| RC1_2548 | RC1_1904 | RC1_2548 | RC1_1904 | Conserved hypothetical protein; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family. | Conserved hypothetical protein; Belongs to the multicopper oxidase YfiH/RL5 family. | 0.869 |
| RC1_2548 | RC1_2547 | RC1_2548 | RC1_2547 | Conserved hypothetical protein; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family. | HIT family proteinspeci; Identified by match to protein family HMM PF00571 match to protein family HMM PF01595 match to protein family HMM PF03471. | 0.601 |
| RC1_2548 | RC1_2874 | RC1_2548 | RC1_2874 | Conserved hypothetical protein; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family. | Conserved hypothetical protein; Identified by match to protein family HMM PF01061. | 0.818 |
| RC1_2548 | murF | RC1_2548 | RC1_0617 | Conserved hypothetical protein; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family. | UDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate--D-alanyl-D-alanyl ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. | 0.744 |
| RC1_2548 | pdxY | RC1_2548 | RC1_3931 | Conserved hypothetical protein; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family. | Pyridoxamine kinase; Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP. | 0.796 |
| RC1_2548 | proC | RC1_2548 | RC1_1898 | Conserved hypothetical protein; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family. | Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. | 0.585 |
| RC1_2548 | rlmN | RC1_2548 | RC1_2562 | Conserved hypothetical protein; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family. | Radical SAM enzyme, Cfr family; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity; Belongs to the radical SAM superfamily. RlmN family. | 0.603 |
| RC1_2548 | rplX | RC1_2548 | RC1_0722 | Conserved hypothetical protein; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family. | Ribosomal protein L24; One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit. | 0.715 |
| RC1_2548 | rpmC | RC1_2548 | RC1_0719 | Conserved hypothetical protein; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family. | Ribosomal protein L29; PF00831 identified by match to protein family HMM PF00297; Belongs to the universal ribosomal protein uL29 family. | 0.726 |
| RC1_2548 | rpmJ | RC1_2548 | RC1_2153 | Conserved hypothetical protein; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family. | Ribosomal protein L36; Identified by match to protein family HMM PF03109; Belongs to the bacterial ribosomal protein bL36 family. | 0.713 |
| RC1_2874 | RC1_2548 | RC1_2874 | RC1_2548 | Conserved hypothetical protein; Identified by match to protein family HMM PF01061. | Conserved hypothetical protein; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family. | 0.818 |
| RC1_2874 | proC | RC1_2874 | RC1_1898 | Conserved hypothetical protein; Identified by match to protein family HMM PF01061. | Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. | 0.452 |
| murF | RC1_2548 | RC1_0617 | RC1_2548 | UDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate--D-alanyl-D-alanyl ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. | Conserved hypothetical protein; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family. | 0.744 |
| pdxY | RC1_2548 | RC1_3931 | RC1_2548 | Pyridoxamine kinase; Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP. | Conserved hypothetical protein; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family. | 0.796 |
| proC | RC1_2548 | RC1_1898 | RC1_2548 | Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. | Conserved hypothetical protein; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family. | 0.585 |
| proC | RC1_2874 | RC1_1898 | RC1_2874 | Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. | Conserved hypothetical protein; Identified by match to protein family HMM PF01061. | 0.452 |
| rlmN | RC1_2548 | RC1_2562 | RC1_2548 | Radical SAM enzyme, Cfr family; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity; Belongs to the radical SAM superfamily. RlmN family. | Conserved hypothetical protein; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family. | 0.603 |
| rplX | RC1_2548 | RC1_0722 | RC1_2548 | Ribosomal protein L24; One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit. | Conserved hypothetical protein; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family. | 0.715 |