node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
RC1_0641 | mutM | RC1_0641 | RC1_3052 | ATP-dependent RNA helicase, DEAD. | formamidopyrimidine-DNA glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates. | 0.852 |
RC1_0641 | uvrC | RC1_0641 | RC1_1885 | ATP-dependent RNA helicase, DEAD. | Excinuclease ABC, C subunit, putative; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision. | 0.607 |
RC1_3051 | RC1_3053 | RC1_3051 | RC1_3053 | Conserved hypothetical protein; Identified by match to protein family HMM PF00015 match to protein family HMM PF00672. | Conserved hypothetical protein; Identified by match to protein family HMM PF00072. | 0.535 |
RC1_3051 | RC1_3054 | RC1_3051 | RC1_3054 | Conserved hypothetical protein; Identified by match to protein family HMM PF00015 match to protein family HMM PF00672. | enoyl-CoA hydratase; Identified by match to protein family HMM PF01545 match to protein family HMM TIGR01297; Belongs to the enoyl-CoA hydratase/isomerase family. | 0.478 |
RC1_3051 | moeB | RC1_3051 | RC1_3050 | Conserved hypothetical protein; Identified by match to protein family HMM PF00015 match to protein family HMM PF00672. | Molybdopterin biosynthesis protein MoeB; Identified by match to protein family HMM PF00515 match to protein family HMM PF07719 match to protein family HMM PF07721. | 0.837 |
RC1_3051 | mutM | RC1_3051 | RC1_3052 | Conserved hypothetical protein; Identified by match to protein family HMM PF00015 match to protein family HMM PF00672. | formamidopyrimidine-DNA glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates. | 0.594 |
RC1_3053 | RC1_3051 | RC1_3053 | RC1_3051 | Conserved hypothetical protein; Identified by match to protein family HMM PF00072. | Conserved hypothetical protein; Identified by match to protein family HMM PF00015 match to protein family HMM PF00672. | 0.535 |
RC1_3053 | RC1_3054 | RC1_3053 | RC1_3054 | Conserved hypothetical protein; Identified by match to protein family HMM PF00072. | enoyl-CoA hydratase; Identified by match to protein family HMM PF01545 match to protein family HMM TIGR01297; Belongs to the enoyl-CoA hydratase/isomerase family. | 0.779 |
RC1_3053 | moeB | RC1_3053 | RC1_3050 | Conserved hypothetical protein; Identified by match to protein family HMM PF00072. | Molybdopterin biosynthesis protein MoeB; Identified by match to protein family HMM PF00515 match to protein family HMM PF07719 match to protein family HMM PF07721. | 0.538 |
RC1_3053 | mutM | RC1_3053 | RC1_3052 | Conserved hypothetical protein; Identified by match to protein family HMM PF00072. | formamidopyrimidine-DNA glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates. | 0.817 |
RC1_3053 | rpsT | RC1_3053 | RC1_3055 | Conserved hypothetical protein; Identified by match to protein family HMM PF00072. | Ribosomal protein S20; Binds directly to 16S ribosomal RNA. | 0.548 |
RC1_3054 | RC1_3051 | RC1_3054 | RC1_3051 | enoyl-CoA hydratase; Identified by match to protein family HMM PF01545 match to protein family HMM TIGR01297; Belongs to the enoyl-CoA hydratase/isomerase family. | Conserved hypothetical protein; Identified by match to protein family HMM PF00015 match to protein family HMM PF00672. | 0.478 |
RC1_3054 | RC1_3053 | RC1_3054 | RC1_3053 | enoyl-CoA hydratase; Identified by match to protein family HMM PF01545 match to protein family HMM TIGR01297; Belongs to the enoyl-CoA hydratase/isomerase family. | Conserved hypothetical protein; Identified by match to protein family HMM PF00072. | 0.779 |
RC1_3054 | moeB | RC1_3054 | RC1_3050 | enoyl-CoA hydratase; Identified by match to protein family HMM PF01545 match to protein family HMM TIGR01297; Belongs to the enoyl-CoA hydratase/isomerase family. | Molybdopterin biosynthesis protein MoeB; Identified by match to protein family HMM PF00515 match to protein family HMM PF07719 match to protein family HMM PF07721. | 0.503 |
RC1_3054 | mutM | RC1_3054 | RC1_3052 | enoyl-CoA hydratase; Identified by match to protein family HMM PF01545 match to protein family HMM TIGR01297; Belongs to the enoyl-CoA hydratase/isomerase family. | formamidopyrimidine-DNA glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates. | 0.757 |
RC1_3054 | rpsT | RC1_3054 | RC1_3055 | enoyl-CoA hydratase; Identified by match to protein family HMM PF01545 match to protein family HMM TIGR01297; Belongs to the enoyl-CoA hydratase/isomerase family. | Ribosomal protein S20; Binds directly to 16S ribosomal RNA. | 0.619 |
coaE | mutM | RC1_2802 | RC1_3052 | dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. | formamidopyrimidine-DNA glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates. | 0.949 |
coaE | nth | RC1_2802 | RC1_2770 | dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. | Endonuclease III, putative; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate. | 0.567 |
coaE | polA | RC1_2802 | RC1_2483 | dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. | DNA polymerase I, putative; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.740 |
moeB | RC1_3051 | RC1_3050 | RC1_3051 | Molybdopterin biosynthesis protein MoeB; Identified by match to protein family HMM PF00515 match to protein family HMM PF07719 match to protein family HMM PF07721. | Conserved hypothetical protein; Identified by match to protein family HMM PF00015 match to protein family HMM PF00672. | 0.837 |