STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hspAHeat shock protein,hsp20 family HspA, putative; PF00011 With many homologs, all are Hsp20 family chaperons, but not characterized; identified by match to protein family HMM PF04055; Belongs to the small heat shock protein (HSP20) family. (163 aa)    
Predicted Functional Partners:
clpA
ATP-dependent Clp protease ATP-binding subunit ClpA; PF07724 PF02861: Clp amino terminal domain; PF07728: ATPase family associated With various cellular activities (AAA); SP:P05444: ClpA homolog protein; identified by match to protein family HMM PF01343; Belongs to the ClpA/ClpB family.
  
 
 0.903
clpB
ATP-dependent chaperone protein ClpB; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family.
  
 
 0.903
htpG
Molecular chaperone,hSP90 family, putative; Molecular chaperone. Has ATPase activity.
  
 
 0.727
dnaK-2
Chaperone protein DnaK, putative; Acts as a chaperone; Belongs to the heat shock protein 70 family.
  
 
 0.709
dnaK
Heat shock protein DnaK, putative; NO HMMs but some uncharacterized homologs identified as HSP70; identified by match to protein family HMM PF02798.
 
 
 0.687
RC1_3206
Conserved hypothetical protein; Identified by match to protein family HMM PF03767.
 
     0.674
hslV
ATP-dependent protease HslV, putative; Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.
   
  
 0.668
grpE
Co-chaperone GrpE, putative; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of [...]
  
 
 0.659
RC1_3001
FxsA cytoplasmic membrane protein; Identified by match to protein family HMM PF00795 match to protein family HMM TIGR00546.
  
    0.652
glnA
Glutamine synthetase, type I.
    
 
 0.631
Your Current Organism:
Rhodospirillum centenum
NCBI taxonomy Id: 414684
Other names: R. centenum SW, Rhodocista centenaria SW, Rhodospirillum centenum SW, Rhodospirillum centenum str. SW, Rhodospirillum centenum strain SW
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.