STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
panB3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. (275 aa)    
Predicted Functional Partners:
panC
Pantoate--beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family.
  
 0.997
panD
Aspartate 1-decarboxylase; Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
 
  
 0.974
panE
2-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.
    
 0.935
ilvD
Dihydroxy-acid dehydratase, putative; Identified by match to protein family HMM PF00581; Belongs to the IlvD/Edd family.
     
 0.926
ilvE-2
Branched-chain-amino-acid aminotransferase, putative; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.
    
 0.921
ilvE
Branched-chain-amino-acid aminotransferase, putative; [Synonyms] Transaminase B.
    
 0.918
nadC
Nicotinate-nucleotide pyrophosphorylase; Identified by match to protein family HMM PF00501; Belongs to the NadC/ModD family.
     0.707
ribD
Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family.
     
 0.538
guaA
GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP.
     
 0.538
RC1_3499
Haloacid dehalogenase-like hydrolase, putative.
       0.508
Your Current Organism:
Rhodospirillum centenum
NCBI taxonomy Id: 414684
Other names: R. centenum SW, Rhodocista centenaria SW, Rhodospirillum centenum SW, Rhodospirillum centenum str. SW, Rhodospirillum centenum strain SW
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.