Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
pyrC-2Dihydroorotase, homodimeric type; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate. (352 aa)    
Predicted Functional Partners:
pyrB
Aspartate carbamoyltransferase; Identified by match to protein family HMM PF01464; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
   
 
 0.987
pyrD
Dihydroorotate oxidase; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
  
 
 0.987
pyrC
Dihydroorotase-like protein; Aspartate carbamoyltransferase 44 kDa Non-catalytic chainthis protein is inactive but is required as a non-catalytic subunit of aspartate transcarbamoylase (ATCase); (by similarity).
    
 0.926
carB
Carbamoyl-phosphate synthase, large subunit; Belongs to the CarB family.
   
  
 0.817
carA
Carbamoyl-phosphate synthase, small subunit; Identified by match to protein family HMM PF00186; Belongs to the CarA family.
   
  
 0.812
RC1_3574
Hypothetical protein; Identified by Glimmer2 putative.
       0.773
pyrE
Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
  
 
 0.752
RC1_3169
HAD-superfamily hydrolase, subfamily IIA; Identified by match to protein family HMM PF00753 match to protein family HMM PF07521.
    
   0.737
upp
Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate.
   
    0.716
purF
Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
  
  
 0.690
Your Current Organism:
Rhodospirillum centenum
NCBI taxonomy Id: 414684
Other names: R. centenum SW, Rhodocista centenaria SW, Rhodospirillum centenum SW, Rhodospirillum centenum str. SW, Rhodospirillum centenum strain SW
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