STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
gshAGlutamate--cysteine ligase; Catalyzes the synthesis of gamma-glutamylcysteine (gamma-GC). Belongs to the glutamate--cysteine ligase type 2 family. EgtA subfamily. (455 aa)    
Predicted Functional Partners:
gshB
Glutathione synthase; Belongs to the prokaryotic GSH synthase family.
    
 0.928
ilvE
Branched-chain-amino-acid aminotransferase, putative; [Synonyms] Transaminase B.
     
  0.900
RC1_0628
5-oxoprolinase; Identified by match to protein family HMM PF01795 match to protein family HMM TIGR00006.
     
  0.900
pepA
Leucyl aminopeptidase PepA, putative; Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N- terminal amino acids from various peptides.
     
  0.900
ilvE-2
Branched-chain-amino-acid aminotransferase, putative; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.
     
  0.900
pepN
Aminopeptidase N, PepN, putative; TIGR02414 PF01433: Peptidase family M1; The M1 family of zinc metallopeptidases contains a number of distinct, well-separated clades of proteins With aminopeptidase activity; identified by match to protein family HMM PF04545 match to protein family HMM TIGR02937.
     
  0.900
ggt
Gamma-glutamyltransferase; Identified by match to protein family HMM PF00355.
     
  0.900
pepB
Leucyl aminopeptidase PepB, putative; In a close position to genes from the similar family; With a good score above the trusted cutoff and uncharacterized homologs; SP|P37095| Peptidase B (EC 3.4.11.23) (Aminopeptidase B); identified by match to protein family HMM PF04389.
     
  0.900
ggt-2
Gamma-glutamyltransferase; Identified by match to protein family HMM PF07486.
     
  0.900
putA
Proline dehydrogenase; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family.
   
 
  0.807
Your Current Organism:
Rhodospirillum centenum
NCBI taxonomy Id: 414684
Other names: R. centenum SW, Rhodocista centenaria SW, Rhodospirillum centenum SW, Rhodospirillum centenum str. SW, Rhodospirillum centenum strain SW
Server load: high (96%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.