node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
gcvH | gcvPA | RC1_3657 | RC1_3658 | Glycine cleavage systemh protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | Glycine cleavage system P-protein subunit 1; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein. | 0.999 |
gcvH | gcvPB | RC1_3657 | RC1_3659 | Glycine cleavage systemh protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | [synonyms] glycine dehydrogenase [decarboxylating] subunit 2 Glycine decarboxylase subunit 2 identified by match to protein family HMM PF01523. | 0.999 |
gcvH | gcvT | RC1_3657 | RC1_3656 | Glycine cleavage systemh protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | Glycine cleavage system T protein; Identified by match to protein family HMM PF07690. | 0.999 |
gcvH | gltB | RC1_3657 | RC1_3193 | Glycine cleavage systemh protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | Glutamate synthase, large subunit. | 0.876 |
gcvH | glyA | RC1_3657 | RC1_1342 | Glycine cleavage systemh protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.981 |
gcvH | lpdA | RC1_3657 | RC1_2259 | Glycine cleavage systemh protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | Dihydrolipoamide dehydrogenase. | 0.989 |
gcvH | pdhD | RC1_3657 | RC1_0122 | Glycine cleavage systemh protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | E3 component of pyruvate and 2-oxoglutarate dehydrogenases complexes identified by match to protein family HMM PF04977. | 0.986 |
gcvPA | gcvH | RC1_3658 | RC1_3657 | Glycine cleavage system P-protein subunit 1; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein. | Glycine cleavage systemh protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | 0.999 |
gcvPA | gcvPB | RC1_3658 | RC1_3659 | Glycine cleavage system P-protein subunit 1; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein. | [synonyms] glycine dehydrogenase [decarboxylating] subunit 2 Glycine decarboxylase subunit 2 identified by match to protein family HMM PF01523. | 0.999 |
gcvPA | gcvT | RC1_3658 | RC1_3656 | Glycine cleavage system P-protein subunit 1; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein. | Glycine cleavage system T protein; Identified by match to protein family HMM PF07690. | 0.999 |
gcvPA | gltB | RC1_3658 | RC1_3193 | Glycine cleavage system P-protein subunit 1; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein. | Glutamate synthase, large subunit. | 0.880 |
gcvPA | glyA | RC1_3658 | RC1_1342 | Glycine cleavage system P-protein subunit 1; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.971 |
gcvPA | hemA | RC1_3658 | RC1_0996 | Glycine cleavage system P-protein subunit 1; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein. | [synonyms] 5-aminolevulinic acid synt Hase Delta-aminolevulinate synt Hase Delta-ALA synthetase identified by match to protein family HMM PF00462 match to protein family HMM TIGR00365. | 0.914 |
gcvPA | hemA-2 | RC1_3658 | RC1_2103 | Glycine cleavage system P-protein subunit 1; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein. | 5-aminolevulinic acid synthase; Identified by match to protein family HMM PF00561 match to protein family HMM TIGR03056. | 0.914 |
gcvPA | lpdA | RC1_3658 | RC1_2259 | Glycine cleavage system P-protein subunit 1; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein. | Dihydrolipoamide dehydrogenase. | 0.938 |
gcvPA | ltaE | RC1_3658 | RC1_1727 | Glycine cleavage system P-protein subunit 1; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein. | Low specificity L-threonine aldolase; Catalyzes the cleavage of L-allo-threonine and L-threonine to glycine and acetaldehyde. | 0.923 |
gcvPA | pdhD | RC1_3658 | RC1_0122 | Glycine cleavage system P-protein subunit 1; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein. | E3 component of pyruvate and 2-oxoglutarate dehydrogenases complexes identified by match to protein family HMM PF04977. | 0.935 |
gcvPB | gcvH | RC1_3659 | RC1_3657 | [synonyms] glycine dehydrogenase [decarboxylating] subunit 2 Glycine decarboxylase subunit 2 identified by match to protein family HMM PF01523. | Glycine cleavage systemh protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | 0.999 |
gcvPB | gcvPA | RC1_3659 | RC1_3658 | [synonyms] glycine dehydrogenase [decarboxylating] subunit 2 Glycine decarboxylase subunit 2 identified by match to protein family HMM PF01523. | Glycine cleavage system P-protein subunit 1; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein. | 0.999 |
gcvPB | gcvT | RC1_3659 | RC1_3656 | [synonyms] glycine dehydrogenase [decarboxylating] subunit 2 Glycine decarboxylase subunit 2 identified by match to protein family HMM PF01523. | Glycine cleavage system T protein; Identified by match to protein family HMM PF07690. | 0.999 |