Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
SFK28421.1AraC-type DNA-binding protein. (294 aa)    
Predicted Functional Partners:
SFL90199.1
Helix-turn-helix domain-containing protein.
 
 
 0.792
SFL08466.1
Glutamate synthase (NADPH/NADH) large chain.
    
 0.736
SFK57996.1
Malate dehydrogenase (oxaloacetate-decarboxylating)(NADP+).
     
 0.711
SFL85753.1
AraC-type DNA-binding protein.
  
     0.705
rpoA
DNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.681
ribB
3,4-dihydroxy 2-butanone 4-phosphate synthase / GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family.
    
  0.657
SFK28476.1
Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline.
    
  0.594
SFK66764.1
Urea carboxylase.
  
 
  0.571
SFL87579.1
Transcriptional regulator GlxA family, contains an amidase domain and an AraC-type DNA-binding HTH domain.
 
 
 0.523
SFL07555.1
Adenylate cyclase.
     
 0.522
Your Current Organism:
Methylorubrum salsuginis
NCBI taxonomy Id: 414703
Other names: CGMCC 1.6474, M. salsuginis, Methylobacterium salsuginis, Methylobacterium salsuginis Wang et al. 2007, NCCB 100140, NCIMB 14847, strain MR
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