STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SFK66362.1HAMP domain-containing protein. (446 aa)    
Predicted Functional Partners:
SFK66207.1
Two-component system, chemotaxis family, sensor kinase CheA.
 
 0.989
SFK66235.1
Purine-binding chemotaxis protein CheW.
 
  0.987
SFL41157.1
Two-component system, chemotaxis family, sensor kinase CheA.
  
 0.964
SFK66470.1
Purine-binding chemotaxis protein CheW.
 
  0.950
SFK88717.1
Two-component system, chemotaxis family, sensor kinase CheA.
  
 0.904
SFK76788.1
PAS domain S-box-containing protein.
  
 0.872
SFK92251.1
PAS domain S-box-containing protein.
  
 0.872
SFL28865.1
PAS domain S-box-containing protein.
  
 0.872
cheB
Two-component system, chemotaxis family, response regulator CheB; Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid. Belongs to the CheB family.
 
  0.869
SFK66500.1
Chemotaxis protein methyltransferase CheR; Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP.
 
 0.868
Your Current Organism:
Methylorubrum salsuginis
NCBI taxonomy Id: 414703
Other names: CGMCC 1.6474, M. salsuginis, Methylobacterium salsuginis, Methylobacterium salsuginis Wang et al. 2007, NCCB 100140, NCIMB 14847, strain MR
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