Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Score
SFL04946.1Two-component system, NtrC family, nitrogen regulation sensor histidine kinase GlnL. (382 aa)    
Predicted Functional Partners:
ntrC
Two-component system, NtrC family, nitrogen regulation response regulator GlnG; Member of the two-component regulatory system NtrB/NtrC, which controls expression of the nitrogen-regulated (ntr) genes in response to nitrogen limitation. Phosphorylated NtrC binds directly to DNA and stimulates the formation of open promoter-sigma54-RNA polymerase complexes.
 0.995
SFL49645.1
Nitrogen regulatory protein P-II family; Belongs to the P(II) protein family.
  
 0.976
SFK88657.1
PAS domain S-box-containing protein.
  
 0.964
SFK54887.1
Nitrogen regulatory protein P-II family; Belongs to the P(II) protein family.
  
 0.936
SFK26586.1
DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains.
 
 0.924
SFL81234.1
PAS domain S-box-containing protein.
  
 0.923
SFL05017.1
tRNA-U20-dihydrouridine synthase; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family.
  
  
 0.917
SFM04039.1
DNA-binding transcriptional response regulator, NtrC family, contains REC, AAA-type ATPase, and a Fis-type DNA-binding domains.
 
 0.897
SFL68421.1
Two-component system, NtrC family, nitrogen regulation response regulator NtrX.
 
 0.895
SFK86887.1
Two-component system, NtrC family, C4-dicarboxylate transport response regulator DctD.
 
 0.892
Your Current Organism:
Methylorubrum salsuginis
NCBI taxonomy Id: 414703
Other names: CGMCC 1.6474, M. salsuginis, Methylobacterium salsuginis, Methylobacterium salsuginis Wang et al. 2007, NCCB 100140, NCIMB 14847, strain MR
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