Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
SFL06958.1Diguanylate cyclase (GGDEF) domain-containing protein. (450 aa)    
Predicted Functional Partners:
SFL38841.1
PAS domain S-box-containing protein.
 
 0.876
SFL71628.1
PAS domain S-box-containing protein.
 
 0.875
SFM00008.1
EAL domain, c-di-GMP-specific phosphodiesterase class I (or its enzymatically inactive variant).
 
 
  0.854
SFL57715.1
EAL domain, c-di-GMP-specific phosphodiesterase class I (or its enzymatically inactive variant).
 
 
  0.853
SFL58690.1
EAL domain-containing protein.
 
 
  0.851
SFK38819.1
EAL domain, c-di-GMP-specific phosphodiesterase class I (or its enzymatically inactive variant).
 
  0.840
SFK92251.1
PAS domain S-box-containing protein.
 
 0.803
SFL28865.1
PAS domain S-box-containing protein.
 
 0.800
SFL06486.1
PAS domain S-box-containing protein.
 
 0.779
SFK76788.1
PAS domain S-box-containing protein.
  
 0.774
Your Current Organism:
Methylorubrum salsuginis
NCBI taxonomy Id: 414703
Other names: CGMCC 1.6474, M. salsuginis, Methylobacterium salsuginis, Methylobacterium salsuginis Wang et al. 2007, NCCB 100140, NCIMB 14847, strain MR
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