STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SFL11719.1Arabinose-5-phosphate isomerase; Belongs to the SIS family. GutQ/KpsF subfamily. (339 aa)    
Predicted Functional Partners:
kdsA
2-dehydro-3-deoxyphosphooctonate aldolase (KDO 8-P synthase); Belongs to the KdsA family.
 
 
 0.985
tal
Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the GPI family.
 
 
 0.944
guaB
IMP dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
    
 0.927
SFL08466.1
Glutamate synthase (NADPH/NADH) large chain.
    
 0.927
SFK80687.1
Ribulose-phosphate 3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family.
  
 
 0.883
lpxK
lipid-A-disaccharide kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).
 
   
 0.879
SFL34188.1
3-deoxy-D-manno-octulosonic-acid transferase; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family.
 
   
 0.878
kdsB
3-deoxy-manno-octulosonate cytidylyltransferase (CMP-KDO synthetase); Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
 
   
 0.878
SFM10111.1
3-deoxy-manno-octulosonate cytidylyltransferase (CMP-KDO synthetase).
 
   
 0.878
lpxB
lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
 
   
 0.873
Your Current Organism:
Methylorubrum salsuginis
NCBI taxonomy Id: 414703
Other names: CGMCC 1.6474, M. salsuginis, Methylobacterium salsuginis, Methylobacterium salsuginis Wang et al. 2007, NCCB 100140, NCIMB 14847, strain MR
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