Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
SFL62869.14-aminobutyrate---pyruvate transaminase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (463 aa)    
Predicted Functional Partners:
bioD
Dethiobiotin synthetase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring.
 
 
 0.935
bioB
Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family.
  
 0.862
SFM04609.1
8-amino-7-oxononanoate synthase.
 
 
 0.765
SFM04582.1
Acyl transferase domain-containing protein.
    
 0.764
SFK66764.1
Urea carboxylase.
  
 
 0.760
SFK30277.1
Guanidinopropionase; Belongs to the arginase family.
 
 
  0.750
SFK94857.1
Aspartate kinase; Belongs to the aspartokinase family.
    
 0.734
SFL08466.1
Glutamate synthase (NADPH/NADH) large chain.
    
 0.732
gcvP
Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family.
    
 0.729
SFL26890.1
HxxPF-repeated domain-containing protein.
  
 
 0.728
Your Current Organism:
Methylorubrum salsuginis
NCBI taxonomy Id: 414703
Other names: CGMCC 1.6474, M. salsuginis, Methylobacterium salsuginis, Methylobacterium salsuginis Wang et al. 2007, NCCB 100140, NCIMB 14847, strain MR
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