| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| SFK39103.1 | SFK39119.1 | SAMN04488125_101512 | SAMN04488125_101513 | uroporphyrin-III C-methyltransferase / precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. | Assimilatory nitrate reductase catalytic subunit; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily. | 0.804 |
| SFK39103.1 | SFK52019.1 | SAMN04488125_101512 | SAMN04488125_102261 | uroporphyrin-III C-methyltransferase / precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. | Hypothetical protein. | 0.837 |
| SFK39103.1 | SFL00522.1 | SAMN04488125_101512 | SAMN04488125_10779 | uroporphyrin-III C-methyltransferase / precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. | NAD(P)H-dependent nitrite reductase flavoprotein subunit. | 0.912 |
| SFK39103.1 | SFL00541.1 | SAMN04488125_101512 | SAMN04488125_10780 | uroporphyrin-III C-methyltransferase / precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. | NAD(P)H-dependent nitrite reductase catalytic subunit; Belongs to the nitrite and sulfite reductase 4Fe-4S domain family. | 0.982 |
| SFK39103.1 | SFL00563.1 | SAMN04488125_101512 | SAMN04488125_10781 | uroporphyrin-III C-methyltransferase / precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. | Nitrite reductase (NADH) large subunit. | 0.820 |
| SFK39103.1 | SFL07964.1 | SAMN04488125_101512 | SAMN04488125_108118 | uroporphyrin-III C-methyltransferase / precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. | Hypothetical protein. | 0.837 |
| SFK39103.1 | SFL58723.1 | SAMN04488125_101512 | SAMN04488125_11888 | uroporphyrin-III C-methyltransferase / precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. | NAD(P)H-nitrite reductase, large subunit. | 0.963 |
| SFK39103.1 | SFL77368.1 | SAMN04488125_101512 | SAMN04488125_12425 | uroporphyrin-III C-methyltransferase / precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. | MFS transporter, NNP family, nitrate/nitrite transporter. | 0.663 |
| SFK39103.1 | cysI | SAMN04488125_101512 | SAMN04488125_11395 | uroporphyrin-III C-methyltransferase / precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. | Sulfite reductase (NADPH) hemoprotein beta-component; Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. Belongs to the nitrite and sulfite reductase 4Fe-4S domain family. | 0.979 |
| SFK39119.1 | SFK39103.1 | SAMN04488125_101513 | SAMN04488125_101512 | Assimilatory nitrate reductase catalytic subunit; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily. | uroporphyrin-III C-methyltransferase / precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. | 0.804 |
| SFK39119.1 | SFL00522.1 | SAMN04488125_101513 | SAMN04488125_10779 | Assimilatory nitrate reductase catalytic subunit; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily. | NAD(P)H-dependent nitrite reductase flavoprotein subunit. | 0.982 |
| SFK39119.1 | SFL00541.1 | SAMN04488125_101513 | SAMN04488125_10780 | Assimilatory nitrate reductase catalytic subunit; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily. | NAD(P)H-dependent nitrite reductase catalytic subunit; Belongs to the nitrite and sulfite reductase 4Fe-4S domain family. | 0.946 |
| SFK39119.1 | SFL00563.1 | SAMN04488125_101513 | SAMN04488125_10781 | Assimilatory nitrate reductase catalytic subunit; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily. | Nitrite reductase (NADH) large subunit. | 0.998 |
| SFK39119.1 | SFL49602.1 | SAMN04488125_101513 | SAMN04488125_11677 | Assimilatory nitrate reductase catalytic subunit; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily. | Multicopper oxidase with three cupredoxin domains (includes cell division protein FtsP and spore coat protein CotA). | 0.668 |
| SFK39119.1 | SFL58723.1 | SAMN04488125_101513 | SAMN04488125_11888 | Assimilatory nitrate reductase catalytic subunit; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily. | NAD(P)H-nitrite reductase, large subunit. | 0.978 |
| SFK39119.1 | SFL77368.1 | SAMN04488125_101513 | SAMN04488125_12425 | Assimilatory nitrate reductase catalytic subunit; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily. | MFS transporter, NNP family, nitrate/nitrite transporter. | 0.952 |
| SFK39119.1 | cysI | SAMN04488125_101513 | SAMN04488125_11395 | Assimilatory nitrate reductase catalytic subunit; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily. | Sulfite reductase (NADPH) hemoprotein beta-component; Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. Belongs to the nitrite and sulfite reductase 4Fe-4S domain family. | 0.810 |
| SFK52019.1 | SFK39103.1 | SAMN04488125_102261 | SAMN04488125_101512 | Hypothetical protein. | uroporphyrin-III C-methyltransferase / precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. | 0.837 |
| SFK52019.1 | SFL00563.1 | SAMN04488125_102261 | SAMN04488125_10781 | Hypothetical protein. | Nitrite reductase (NADH) large subunit. | 0.437 |
| SFK52019.1 | SFL58723.1 | SAMN04488125_102261 | SAMN04488125_11888 | Hypothetical protein. | NAD(P)H-nitrite reductase, large subunit. | 0.951 |