Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
SFL90059.1Transcriptional regulator, LysR family; Belongs to the LysR transcriptional regulatory family. (288 aa)    
Predicted Functional Partners:
SFL00468.1
DNA-binding transcriptional regulator, LysR family; Belongs to the LysR transcriptional regulatory family.
  
     0.665
SFK64498.1
DNA-binding transcriptional regulator, LysR family; Belongs to the LysR transcriptional regulatory family.
  
     0.652
rpoA
DNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
 
 0.590
rpoB
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.564
rpoZ
DNA-directed RNA polymerase subunit omega; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
    
 
 0.562
SFL90082.1
Hypothetical protein; Belongs to the pirin family.
       0.544
rpoC
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.524
SFK39256.1
DNA-binding transcriptional regulator, LysR family; Belongs to the LysR transcriptional regulatory family.
  
     0.488
SFL90031.1
Nicotinamidase-related amidase.
       0.464
SFL25477.1
Transcriptional regulator, LysR family; Belongs to the LysR transcriptional regulatory family.
  
     0.425
Your Current Organism:
Methylorubrum salsuginis
NCBI taxonomy Id: 414703
Other names: CGMCC 1.6474, M. salsuginis, Methylobacterium salsuginis, Methylobacterium salsuginis Wang et al. 2007, NCCB 100140, NCIMB 14847, strain MR
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