Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SFL91028.1Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase. (492 aa)    
Predicted Functional Partners:
mutS
DNA mismatch repair protein MutS; This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.
  
 0.964
SFL91058.1
Z1 domain-containing protein.
 
   
 0.955
SFL91085.1
Putative PD-(D/E)XK family member.
 
     0.955
SFL91116.1
AIPR protein.
 
  
 0.882
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
   
 0.860
SFK55527.1
DNA polymerase family A.
   
 0.860
SFK88477.1
ATP-dependent DNA helicase RecQ.
  
 0.845
SFK88374.1
DNA polymerase-3 subunit beta.
   
 0.833
SFL18198.1
DNA polymerase-3 subunit beta.
   
 0.833
SFL99832.1
DNA (cytosine-5)-methyltransferase 1; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.
 
  
 0.748
Your Current Organism:
Methylorubrum salsuginis
NCBI taxonomy Id: 414703
Other names: CGMCC 1.6474, M. salsuginis, Methylobacterium salsuginis, Methylobacterium salsuginis Wang et al. 2007, NCCB 100140, NCIMB 14847, strain MR
Server load: medium (44%) [HD]